3.6.1.11: exopolyphosphatase

This is an abbreviated version!
For detailed information about exopolyphosphatase, go to the full flat file.

Word Map on EC 3.6.1.11

Reaction

(Polyphosphate)n
+
H2O
=
(polyphosphate)n-1
+
phosphate

Synonyms

More, metaphosphatase, phosphatase, exopoly-, acid phosphoanhydride phosphohydrolase, Gra-Pase, exopoly(P)ase, ExopolyPase, PPX, Ppn1, LmPPX, h-prune, nuclear exopolyphosphatase, high molecular mass exopolyphosphatase, polyphosphate phosphohydrolase, high molecular weight exopolyphosphatase, 40 kD exopolyphosphatase, polyphosphate-phosphohydrolase, major cytosolic exopolyphosphatase PPX1, vacuolar exopolyphosphatase, exopolyphosphatase 1, exopolyphosphatase 2, PPXI, membrane-bound exopolyphosphatase, 40-kDa-exopolyphosphatase, high-molecular exopolyphosphatase, polyphosphate phosphatase, Ppx protein, PPX1, Nudix hydrolase, exopolyphosphatase, PPX2, NMB1467, MT0516, CT0099, CT1713, CJJ81176_0377, CJJ81176_1251, Rv0496, paPpx, TbNH4, TbDcp2, Tb927.6.2670, TbNH2, Tb927.5.4350, YHR201C, ZmPPX, Za10_0559, PPXMsed, Ppx/GppA phosphatase, Msed_0981, ecPpx

ECTree

     3 Hydrolases
         3.6 Acting on acid anhydrides
             3.6.1 In phosphorus-containing anhydrides
                3.6.1.11 exopolyphosphatase

Disease

Disease on EC 3.6.1.11 - exopolyphosphatase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Infections
Catalytic properties of wheat phytase that favorably degrades long-chain inorganic polyphosphate.
Leukemia
Inorganic polyphosphate in human osteoblast-like cells.
Polyphosphate Is a Novel Pro-inflammatory Regulator of Mast Cells and Is Located in Acidocalcisomes.
Neoplasm Metastasis
Human metastasis regulator protein H-prune is a short-chain exopolyphosphatase.
Neoplasms
h-Prune is associated with poor prognosis and epithelial-mesenchymal transition in patients with colorectal liver metastases.
Inositol phosphate recycling regulates glycolytic and lipid metabolism that drives cancer aggressiveness.
Sepsis
Bacterial polyphosphates interfere with the innate host defense to infection.
Starvation
Functional Insights Into the Role of gppA in (p)ppGpp Metabolism of Vibrio cholerae.
Requirement of the exopolyphosphatase gene for cellular acclimation to phosphorus starvation in a cyanobacterium, Synechocystis sp. PCC 6803.
Tuberculosis
Deficiency of the novel exopolyphosphatase Rv1026/PPX2 leads to metabolic downshift and altered cell wall permeability in Mycobacterium tuberculosis.
Establishing Virulence Associated Polyphosphate Kinase 2 as a drug target for Mycobacterium tuberculosis.
Polyphosphate deficiency affects the sliding motility and biofilm formation of Mycobacterium smegmatis.
The role of the novel exopolyphosphatase MT0516 in Mycobacterium tuberculosis drug tolerance and persistence.
The Two PPX-GppA Homologues from Mycobacterium tuberculosis Have Distinct Biochemical Activities.
[Progress in polyphosphate and related metabolizing enzymes].