3.6.1.11: exopolyphosphatase This is an abbreviated version! For detailed information about exopolyphosphatase, go to the full flat file .
Reaction
(Polyphosphate)n +
H2O =
(polyphosphate)n-1 +
phosphate
Synonyms 40 kD exopolyphosphatase, 40-kDa-exopolyphosphatase, acid phosphoanhydride phosphohydrolase, CJJ81176_0377, CJJ81176_1251, CT0099, CT1713, ecPpx, exopoly(P)ase, ExopolyPase, exopolyphosphatase, exopolyphosphatase 1, exopolyphosphatase 2, Gra-Pase, h-prune, high molecular mass exopolyphosphatase, high molecular weight exopolyphosphatase, high-molecular exopolyphosphatase, LmPPX, major cytosolic exopolyphosphatase PPX1, membrane-bound exopolyphosphatase, metaphosphatase, More, Msed_0981, MT0516, NMB1467, nuclear exopolyphosphatase, Nudix hydrolase, paPpx, phosphatase, exopoly-, polyphosphate phosphatase, polyphosphate phosphohydrolase, polyphosphate-phosphohydrolase, Ppn1, PPX, Ppx protein, Ppx/GppA phosphatase, PPX1, PPX2, PPXI, PPXMsed, Rv0496, Tb927.5.4350, Tb927.6.2670, TbDcp2, TbNH2, TbNH4, vacuolar exopolyphosphatase, YHR201C, Za10_0559, ZmPPX
ECTree
Activating Compound
Activating Compound on EC 3.6.1.11 - exopolyphosphatase
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(NH4)2SO4
-
50 mM, stimulates
ammonium chloride
200 mM, stimulates almost twofold in the presence and absence of 0.1 mM Co2+
carbonyl cyanide-4-trifluoromethoxyphenylhydrazone
-
-
Dimethylamine
-
9% activation compared to NH4+
dithiothreitol
-
about 50% stimulation of activity at 1 mM
methylamine
-
28% activation compared to NH4+
polylysine
100 mg/l, 2fold activity enhancement
Pyruvic acid
-
activates PPX1, activation is inhibited KCN
succinic acid
-
activates PPX1, activation is inhibited KCN
trimethylamine
-
5% activation compared to NH4+
additional information
CaCl2, BaCl2, CuSO4, and SnCl2 do not show any activating effect on PPX2
-
additional information
CaCl2, BaCl2, CuSO4, and SnCl2 do not show any activating effect on PPX2
-
additional information
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CaCl2, BaCl2, CuSO4, and SnCl2 do not show any activating effect on PPX2
-
additional information
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no activation by NAD+
-
additional information
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nuclear polyphosphates decrease and activity of exopolyphosphatase increases after embryo cellularization until the end of embryogenesis
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additional information
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RNA does not alter the nuclear exopolyphosphatase activity
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additional information
RNA does not alter the nuclear exopolyphosphatase activity
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additional information
the activity of PPX1 is not affected by cAMP, deoxynucleoside triphosphates, ATP, sodium diphosphate, L-arginine, or by long polyanions such as heparin or RNA
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additional information
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the activity of PPX1 is not affected by cAMP, deoxynucleoside triphosphates, ATP, sodium diphosphate, L-arginine, or by long polyanions such as heparin or RNA
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