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3.6.1.1: inorganic diphosphatase

This is an abbreviated version!
For detailed information about inorganic diphosphatase, go to the full flat file.

Word Map on EC 3.6.1.1

Reaction

diphosphate
+
H2O
= 2 phosphate

Synonyms

acid PPase, AT727_13205, AtPPA1, AtPPsPase1, BT2127, CBS-PPase, CBS-PPase1, chloroplast inorganic pyrophosphatase 1, class A type PPA, cobalt-dependent inorganic pyrophosphatase, CPE2055, cytosolic PPase, D1C enzyme, dhPPase, E-PPase, EcPpA, EcPPiase, ehPPase, family I inorganic pyrophosphatase, family I PPase, family I pyrophosphatase, family II inorganic pyrophosphatase, family II PPase, H+-PPase, H+-pyrophosphatase, H+-translocating/vacuolar inorganic pyrophosphatase, Hpp1 protein, HVO_0729, HvPPA, hyperthermophilic inorganic pyrophosphatase, inorganic diphosphatase, inorganic PPase, inorganic pyrophosphatase, inorganic pyrophosphatase 1, inorganic pyrophosphatase-like protein, inorganic pyrophosphorylase, IPP, IPP1, Ipp1p, IPPase, LHPPase, M-PPase, manganese-dependent inorganic pyrophosphatase, MazG, MdPPa, membrane-integral inorganic pyrophosphatase, membrane-integral pyrophosphatase, miPPase, mitochondrial pyrophosphatase, Mn2+-bound canonical Family II PPase, More, Mtb PPiase, Mthe_0236, MtPPA1, MtPPiase, nucleotide-regulated pyrophosphatase, OVP1, p26.1a, p26.1b, PfPPase, PH1907, Pho-PPase, phospholysine phosphohistidine inorganic pyrophosphate phosphatase, phosphoprotein p26.1, PPA, PPA1, PpaC, PPase, PPase 1, PPase 2, ppase-1, PPase-2, PPase1, PPase2, PPase4, PPias, PPIase, proton-translocating inorganic pyrophosphatase, PYP-1, pyrophosphatase, pyrophosphatase, inorganic, Pyrophosphate phospho-hydrolase, pyrophosphate phospho-hydrolase 1, Pyrophosphate phosphohydrolase, Pyrophosphate-energized inorganic pyrophosphatase, RmPPase, Rv3628, siPPiase, soluble inorganic pyrophosphatase, soluble inorganic pyrophosphatase 2, soluble pyrophosphatase, soluble-type yeast PPase, sPPAse, ST2226, Tc-sPPase, TC004566, TcasGA2_TC004566, TgPPase, ThPP1, Tm-PPase, TM0913, V-PPase, vacuolar H(+)-PPase, vacuolar H(+)-pyrophosphatase, vacuolar H+-pyrophosphatase, vacuolar H+-translocating inorganic pyrophosphatase, vacuolar H+-translocating pyrophosphatase, vacuolar pyrophosphatase, VHP, VP1, VSP, VVPP1

ECTree

     3 Hydrolases
         3.6 Acting on acid anhydrides
             3.6.1 In phosphorus-containing anhydrides
                3.6.1.1 inorganic diphosphatase

Expression

Expression on EC 3.6.1.1 - inorganic diphosphatase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
addition of phosphate and/or diphosphate, to the semi-synthetic media results in about twofold increase in the acid PPase activity. However, in the nutrient broth, no induction is observed even when diphosphate is supplemented
expression profiles of the ThPP1 gene in response to alkali stress, overview. Expression of the ThPP1 gene in Thellungiella halophila significantly increases under alkali treatment, at pH 8.5, the expression level of the ThPP1 gene is increased by 1.41fold, and at pH 9.0, the relative expression of the ThPP1 gene increased by 2.05fold compared to normal treatment
gene MdVHP1 expression is induced by salt, PEG-mediated osmotic stress, cold and heat in apple in vitro shoot cultures. MdVHP1 expression shows a similar pattern in different apple tissues, but different change dynamics in response to abiotic stresses, compared with MdVHP2. Gene MdVHP2 expression is strongly induced by drought, cold and heat, with different change dynamics compared with MdVHP1
gene MdVHP2 is negatively regulated in general by salt stress
inorganic pyrophosphatase 1 is upregulated in the chick cerebellum treated with methimazole at a dose of 0.02 mM/egg on day 14
-
older mice show a significant increase in the expression and activity of the enzyme as compared to younger ones. Short-term fasting of 24 h increases the expression and activity of the enzyme in the liver of both young (20%) and old (19%) mice which are reversed upon 24 h of re-feeding them
the enzyme is induced by phosphate starvation
trichostatin A and Sp1 induce pyrophosphatase 1 promoter activity and protein expression