3.5.4.5: cytidine deaminase
This is an abbreviated version!
For detailed information about cytidine deaminase, go to the full flat file.
Word Map on EC 3.5.4.5
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3.5.4.5
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hypermutation
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immunoglobulin
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deamination
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ige
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b-cells
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lymphocyte
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leukemia
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lymphoma
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diversification
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class-switched
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apobec3g
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immunodeficiency
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deaminases
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uracil
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gemcitabine
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single-stranded
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uridine
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isotype
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virion
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arabinoside
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cytarabine
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retroviruses
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ssdna
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glycosylase
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lymphomagenesis
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deoxyuridine
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cd40l
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encapsidation
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1-beta-d-arabinofuranosylcytosine
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deoxycytidylate
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c-to-u
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blimp-1
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nickase
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mrna-editing
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capecitabine
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polypeptide-like
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uracil-dna
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microhomology
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abasic
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medicine
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5-aza-cdr
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drug development
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protospacer
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diagnostics
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5'-deoxy-5-fluorouridine
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5\'-dfur
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plasmablast
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retroelements
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zebularine
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ara-ctp
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t-independent
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anti-cd40
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unmutated
- 3.5.4.5
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hypermutation
- immunoglobulin
-
deamination
- ige
- b-cells
- lymphocyte
- leukemia
- lymphoma
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diversification
-
class-switched
- apobec3g
- immunodeficiency
- deaminases
- uracil
- gemcitabine
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single-stranded
- uridine
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isotype
- virion
- arabinoside
- cytarabine
- retroviruses
- ssdna
- glycosylase
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lymphomagenesis
- deoxyuridine
- cd40l
-
encapsidation
- 1-beta-d-arabinofuranosylcytosine
- deoxycytidylate
-
c-to-u
-
blimp-1
-
nickase
-
mrna-editing
- capecitabine
-
polypeptide-like
-
uracil-dna
-
microhomology
-
abasic
- medicine
-
5-aza-cdr
- drug development
-
protospacer
- diagnostics
- 5'-deoxy-5-fluorouridine
-
5\'-dfur
-
plasmablast
-
retroelements
- zebularine
- ara-ctp
-
t-independent
-
anti-cd40
-
unmutated
Reaction
Synonyms
activation-induced cytidine deaminase, AICDA, canine hepatic cyd deaminase, CDA, CDABcald, CDABpsy, CDABsub, CDase, CDD, CR deaminase, cyd deaminase, Cytidine aminohydrolase, cytidine deaminase, cytidine/2'-deoxycytidine aminohydrolase, cytosine nucleoside deaminase, DCD, dCDA, deoxycytidine deaminase, EC 3.5.4.14, mammalian deminase, T-CDA, yeast cytidine deaminase
ECTree
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Cloned
Cloned on EC 3.5.4.5 - cytidine deaminase
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cdd gene cloned and amplified with pTK148, cloning vector pBR322, enzyme overexpression in Escherichia coli C600
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cdd genes cloned and characterized
cDNA coding for AT-CDA1 amplified, subcloned into pTrc99-A, induced and expressed and overproduced in Escherichia coli SO5201
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expressed in Escherichia coli BL21(DE3) cells
expressed in Escherichia coli Rosetta(DE3)pLysS cells
expression in Escherichia coli
expression of wild-type and mutant enzymes in Escherichia coli, complementation of enzyme enzyme-deficient strain by the wild-type enzyme and mutants Y60G, R68Q, and R68G, not by F33 and F137A mutants
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functional expression of the human enzyme in murine fibroblast cell lines 3T3 NIH and 3T3-CD3-V5 cells, and in the murine lymphocytic leukemia cell line L1210
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gene At-cda1, located on chromosome 2 PCR amplified, cloned and sequenced, expressed in Escherichia coli BL21(D3)
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overexpression of wild-type enzyme and mutant enzymes R56A, R56Q and C53H/R56Q in Escherichia coli
SO268 harboring plasmid pSO143 containing the B. subtilis cytidine deaminase gene
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