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3.5.4.16: GTP cyclohydrolase I

This is an abbreviated version!
For detailed information about GTP cyclohydrolase I, go to the full flat file.

Word Map on EC 3.5.4.16

Reaction

GTP
+
H2O
=
formate
 +
7,8-dihydroneopterin 3'-triphosphate

Synonyms

dihydroneopterin triphosphate synthase, FelE, folE, GCH, GCH-1, GCH1, GCHI, GCYH-IA, GCYH-IB, GTP 8-formylhydrolase, GTP CHase I, GTP cyclohydrolase, GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP cyclohydrolase IA, GTP cyclohydrolase IB, GTP cyclohydrolase-1, GTP-CH, GTP-CH-I, GTP-CH1, GTP-cyclohydrolase 1, GTP-cyclohydrolase I, GTPCH, GTPCH I, GTPCH-1, GTPCH1, GTPCHI, guanosine 5'-triphosphate-cyclohydrolase I, guanosine triphosphate 8-deformylase, guanosine triphosphate cyclohydrolase, guanosine triphosphate cyclohydrolase 1, guanosine triphosphate cyclohydrolase I, guanosine-5'-triphosphate cyclohydrolase 1, hydrolase, guanosine triphosphate cyclo-, MptA, Punch, Punch protein

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.4 In cyclic amidines
                3.5.4.16 GTP cyclohydrolase I

Source Tissue

Source Tissue on EC 3.5.4.16 - GTP cyclohydrolase I

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
adipocyte cell line
Manually annotated by BRENDA team
GCHI mRNA level is highest in unripe fruit
Manually annotated by BRENDA team
-
the black markings on the larva during fourth ecdysis are involving the GTPCHI activity
Manually annotated by BRENDA team
-
transfected with a tet-off plasmid and a plasmid encoding human GCH1, the stable clone is named tet-GCH cell
Manually annotated by BRENDA team
additional information