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3.5.4.13: dCTP deaminase

This is an abbreviated version!
For detailed information about dCTP deaminase, go to the full flat file.

Word Map on EC 3.5.4.13

Reaction

dCTP
+
H2O
=
dUTP
 +
NH3

Synonyms

5-methyl-dCTP deaminase, DCD:DUT, dcdB, dCMP-dCTP deaminase, dCTP deaminase, dCTP deaminase:deoxyuridine triphosphatase, dCTP deaminase:dUTPase, deoxycytidine triphosphate deaminase

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.4 In cyclic amidines
                3.5.4.13 dCTP deaminase

Reference

topprint

Reference on EC 3.5.4.13 - dCTP deaminase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Wang, R.Y.H.; Ehrlich, M.
5-Methyl-dCTP deaminase induced by bacteriophage XP-12
J. Virol.
42
42-48
1982
Xanthomonas oryzae
Manually annotated by BRENDA team
Neuhard, J.
dCTP Deaminase from Salmonella typhimurium
Methods Enzymol.
51
418-423
1978
Salmonella enterica subsp. enterica serovar Typhimurium
Manually annotated by BRENDA team
Beck, C.F.; Eisenhardt, A.R.; Neuhard, J.
Deoxycytidine triphosphate deaminase of Salmonella typhimurium
J. Biol. Chem.
250
609-616
1975
Salmonella enterica subsp. enterica serovar Typhimurium
Manually annotated by BRENDA team
Price, A.R.
Bacteriophage PBS2-induced deoxycytidine triphosphate deaminase in Bacillus subtilis
J. Virol.
14
1314-1317
1974
Bacillus subtilis
Manually annotated by BRENDA team
Tomita, F.; Takahashi, I.
A novel enzyme, dCTP deaminase, found in Bacillus subtilis infected with phage PBS1
Biochim. Biophys. Acta
179
18-27
1969
Bacillus subtilis
Manually annotated by BRENDA team
Wang, L.; Weiss, B.
Dcd (dCTP deaminase) gene of Escherichia coli: Mapping, cloning, sequencing, and identification as a locus of suppressors of lethal dut (dUTPase) mutations
J. Bacteriol.
174
5647-5653
1992
Escherichia coli, Salmonella enterica subsp. enterica serovar Typhimurium
Manually annotated by BRENDA team
Speed, R.R.; Winkler, H.H.
Deamination of deoxycytidine nucleotides by the obligate intracytopplasmic bacterium Rickettsia prowazekii
J. Bacteriol.
173
4902-4903
1991
Escherichia coli, Rickettsia prowazekii, Salmonella enterica subsp. enterica serovar Typhimurium
Manually annotated by BRENDA team
Weiss, B.; Wang, L.
De novo synthesis of thymidylate via deoxycytidine in dcd (dCTP deaminase) mutants of Escherichia coli
J. Bacteriol.
176
2194-2199
1994
Escherichia coli
Manually annotated by BRENDA team
Estevenon, A.M.; Kooistra, J.; Sicard, N.
An Escherichia coli strain deficient for both exonuclease V and deoxycytidine triphosphate deaminase shows enhanced sensitivity to ionizing radiation
Mol. Gen. Genet.
246
514-518
1995
Escherichia coli
Manually annotated by BRENDA team
Huffman, J.L.; Li, H.; White, R.H.; Tainer, J.A.
Structural basis for recognition and catalysis by the bifunctional dCTP deaminase and dUTPase from Methanococcus jannaschii
J. Mol. Biol.
331
885-896
2003
Methanocaldococcus jannaschii (Q57872), Methanocaldococcus jannaschii
Manually annotated by BRENDA team
Bjornberg, O.; Neuhard, J.; Nyman, P.O.
A bifunctional dCTP deaminase-dUTP nucleotidohydrolase from the hyperthermophilic archaeon Methanocaldococcus jannaschii
J. Biol. Chem.
278
20667-20672
2003
Methanocaldococcus jannaschii
Manually annotated by BRENDA team
Johansson, E.; Fan?, M.; Bynck, J.H.; Neuhard, J.; Larsen, S.; Sigurskjold, B.W.; Christensen, U.; Willemoes, M.
Structures of dCTP deaminase from Escherichia coli with bound substrate and product: reaction mechanism and determinants of mono- and bifunctionality for a family of enzymes
J. Biol. Chem.
280
3051-3059
2005
Escherichia coli (P28248), Escherichia coli
Manually annotated by BRENDA team
Thymark, M.; Johansson, E.; Larsen, S.; Willemoes, M.
Mutational analysis of the nucleotide binding site of Escherichia coli dCTP deaminase
Arch. Biochem. Biophys.
470
20-26
2008
Escherichia coli (P28248), Escherichia coli
Manually annotated by BRENDA team
Johansson, E.; Thymark, M.; Bynck, J.H.; Fanoe, M.; Larsen, S.; Willemoes, M.
Regulation of dCTP deaminase from Escherichia coli by nonallosteric dTTP binding to an inactive form of the enzyme
FEBS J.
274
4188-4198
2007
Escherichia coli (P28248), Escherichia coli
Manually annotated by BRENDA team
Helt, S.S.; Thymark, M.; Harris, P.; Aagaard, C.; Dietrich, J.; Larsen, S.; Willemoes, M.
Mechanism of dTTP inhibition of the bifunctional dCTP deaminase:dUTPase encoded by Mycobacterium tuberculosis
J. Mol. Biol.
376
554-569
2008
Mycobacterium tuberculosis (P9WP17), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WP17)
Manually annotated by BRENDA team
Zhang, Y.; Maley, F.; Maley, G.F.; Duncan, G.; Dunigan, D.D.; Van Etten, J.L.
Chloroviruses encode a bifunctional dCMP-dCTP deaminase that produces two key intermediates in dTTP formation
J. Virol.
81
7662-7671
2007
Paramecium bursaria Chlorella virus 1 (O41078), Paramecium bursaria Chlorella virus 1
Manually annotated by BRENDA team
Oehlenschlaeger, C.B.; L?vgreen, M.N.; Reinauer, E.; Lehtinen, E.; Pind, M.L.; Harris, P.; Martinussen, J.; Willemoes, M.
Bacillus halodurans strain C125 encodes and synthesizes enzymes from both known pathways to form dump directly from cytosine deoxyribonucleotides
Appl. Environ. Microbiol.
81
3395-3404
2015
Halalkalibacterium halodurans (Q9KFV3), Halalkalibacterium halodurans C-125 (Q9KFV3)
Manually annotated by BRENDA team