3.5.4.13: dCTP deaminase
This is an abbreviated version!
For detailed information about dCTP deaminase, go to the full flat file.
Word Map on EC 3.5.4.13
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3.5.4.13
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dttp
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deamination
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thymidylate
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jannaschii
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thymine
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uracil
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methanocaldococcus
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bifunctionality
- 3.5.4.13
- dttp
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deamination
- thymidylate
- jannaschii
- thymine
- uracil
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methanocaldococcus
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bifunctionality
Reaction
Synonyms
5-methyl-dCTP deaminase, DCD:DUT, dcdB, dCMP-dCTP deaminase, dCTP deaminase, dCTP deaminase:deoxyuridine triphosphatase, dCTP deaminase:dUTPase, deoxycytidine triphosphate deaminase
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Natural Substrates Products
Natural Substrates Products on EC 3.5.4.13 - dCTP deaminase
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REACTION DIAGRAM
dCMP + H2O
dUMP + NH3
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dUMP is a key intermediate in the synthesis of dTTP and subsequently of DNA synthesis
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additional information
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bifunctionality of enzyme avoids release of toxic UTP within cells
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dCTP + H2O
dUTP + NH3
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dUMP is required for dTMP synthesis via hydrolysis of UTP by dUTPase to dUMP
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