3.5.4.13: dCTP deaminase
This is an abbreviated version!
For detailed information about dCTP deaminase, go to the full flat file.
Word Map on EC 3.5.4.13
-
3.5.4.13
-
dttp
-
deamination
-
thymidylate
-
jannaschii
-
thymine
-
uracil
-
methanocaldococcus
-
bifunctionality
- 3.5.4.13
- dttp
-
deamination
- thymidylate
- jannaschii
- thymine
- uracil
-
methanocaldococcus
-
bifunctionality
Reaction
Synonyms
5-methyl-dCTP deaminase, DCD:DUT, dcdB, dCMP-dCTP deaminase, dCTP deaminase, dCTP deaminase:deoxyuridine triphosphatase, dCTP deaminase:dUTPase, deoxycytidine triphosphate deaminase
ECTree
3.5.4.13 dCTP deaminaseAdvanced search results
results (
results (Results
in table
2
15936
22
72
14
Inhibitors
Inhibitors on EC 3.5.4.13 - dCTP deaminase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
INHIBITOR 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
H4dUMP
inhibits both dCTP and dCMP deaminase activities
PDRP
inhibits both dCTP and dCMP deaminase activities
dTTP
inhibits by increasing the kcat several fold, mutants S111T and E138D are less sensitive to dTTP, overview
dTTP
inhibits the enzyme in a nonallosterical way, cooperative kinetics are imposed by a dTTP-dependent lag of product formation observed in presteady-state kinetics, the lag may be derived from a slow equilibration between an inactive and an active conformation of dCTP deaminase represented by the dTTP complex and the dUTP/dCTP complex, respectively, steady-state kinetic analysis of dTTP inhibition, overview
dTTP
the inhibitor has a regukatory function for the bifunctional enzyme, mechanism of regulation by conformational changes, overview
dTTP
inhibits dCMP deamination, feedback inhibition
