Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

3.5.3.6: arginine deiminase

This is an abbreviated version!
For detailed information about arginine deiminase, go to the full flat file.

Word Map on EC 3.5.3.6

Reaction

L-arginine
+
H2O
=
L-citrulline
+
NH3

Synonyms

ADI, ArcA, arcA-1, arcA-2, arginine deiminase, arginine dihydrolase, arginine-degrading enzyme, citrulline iminase, deiminase, arginine, L-arginine deiminase, LADI, lymphocyte blastogenesis inhibitory factor, More, PaADI, PAD, PAD2, peptidylarginine deiminase, PpADI, Streptococcal acid glycoprotein

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.3 In linear amidines
                3.5.3.6 arginine deiminase

Substrates Products

Substrates Products on EC 3.5.3.6 - arginine deiminase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
agmatine-L-Arg + H2O
N5-carbamoyl-N2-[4-(carbamoylamino)butyl]-L-ornithine + NH3
show the reaction diagram
-
3.2% activity compared to L-Arg
-
-
?
benzoyl-L-arginine ethyl ester + H2O
benzoyl-L-citrulline ethyl ester + NH3
show the reaction diagram
Boc-Gln-Arg-Arg-MCA + H2O
? + NH3
show the reaction diagram
-
-
-
-
?
bradykinin-L-Arg + H2O
bradykinin-L-citrulline + NH3
show the reaction diagram
-
18.8% activity compared to L-Arg
-
-
?
D-Arg + H2O
?
show the reaction diagram
-
26.4% activity compared to L-Arg
-
-
?
D-Arg + H2O
D-citrulline + NH3
show the reaction diagram
-
0.38% of the activity with L-Arg
-
-
?
guanidine + H2O
urea + NH3
show the reaction diagram
-
-
-
-
?
homoarginine + H2O
(2S)-2-amino-6-[(aminocarbonyl)amino]hexanoic acid + NH3
show the reaction diagram
-
50% activity compared to L-Arg
-
-
?
KRPPGFSPL + H2O
L-lysyl-N5-carbamoyl-L-ornithyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-L-leucine + NH3
show the reaction diagram
-
3.1% activity compared to L-Arg
-
-
?
L-alanine + H2O
? + NH3
show the reaction diagram
L-alpha-amino-beta-guanidinepropionic acid + H2O
2-amino-3-carbamoylpropionic acid + NH3
show the reaction diagram
-
-
-
-
?
L-alpha-amino-beta-guanidinopropionic acid + H2O
2-amino-3-carbamoylpropionic acid + NH3
show the reaction diagram
-
-
-
-
?
L-alpha-amino-gamma-guanidinobutyric acid + H2O
2-amino-4-carbamoylbutanoic acid + NH3
show the reaction diagram
-
-
-
-
?
L-Arg + H2O
citrulline + NH3
show the reaction diagram
L-Arg + H2O
L-citrulline + NH3
show the reaction diagram
L-arginine + H2O
L-citrulline + NH3
show the reaction diagram
L-arginine ethyl ester + H2O
?
show the reaction diagram
L-arginine hydroxamate + H2O
?
show the reaction diagram
-
68.2% activity compared to L-Arg
-
-
?
L-argininic acid + H2O
(2S)-5-[(aminocarbonyl)amino]-2-hydroxypentanoic acid + NH3
show the reaction diagram
-
0.032% of the activity with L-Arg
-
-
?
L-canavanine + H2O
(2S)-2-amino-4-[[(aminocarbonyl)amino]oxy]butanoic acid + NH3
show the reaction diagram
-
2.3% of the activity with L-Arg
-
-
?
L-canavanine + H2O
O-ureido-L-homoserine + NH3
show the reaction diagram
L-canavanine + H2O
O-ureidohomoserine + NH3
show the reaction diagram
-
via enzyme Cys-bound S-alkyl-thiouronium intermediate, residues Asp166 and Asp280 are involved, overview
product identification by mass spectrometry
-
?
L-canavanine-L-Arg + H2O
O-ureido-L-homoserine + NH3
show the reaction diagram
-
2.5% activity compared to L-Arg
-
-
?
L-homoarginine + H2O
(2S)-2-amino-6-[(aminocarbonyl)amino]hexanoic acid + NH3
show the reaction diagram
-
0.05% of the activity with L-Arg
-
-
?
L-lysine + H2O
? + NH3
show the reaction diagram
L-nitroarginine + H2O
NH3 + nitrocitrulline
show the reaction diagram
-
-
-
-
?
L-Pro-L-Arg-L-Phe + H2O
?
show the reaction diagram
-
3.4% activity compared to L-Arg
-
-
?
L-Pro-L-Phe-L-Arg + H2O
?
show the reaction diagram
-
78.2% activity compared to L-Arg
-
-
?
N-alpha-benzoyl-L-arginine + H2O
N-alpha-benzoyl-L-citrulline + NH3
show the reaction diagram
N-alpha-benzoyl-L-arginine ethyl ester + H2O
N-alpha-benzoyl-L-citrulline methyl ester + NH3
show the reaction diagram
-
-
-
?
Nalpha-benzoyl-L-arginine + H2O
?
show the reaction diagram
Nalpha-methyl-L-Arg + H2O
Nalpha-methyl-L-citrulline + NH3
show the reaction diagram
-
0.75% of the activity with L-Arg
-
-
?
Nomega-amino-Arg + H2O
L-citrulline + hydrazine
show the reaction diagram
-
-
-
?
Nomega-amino-L-arginine + H2O
hydrazine + L-citrulline
show the reaction diagram
Nomega-amino-L-arginine + H2O
L-citrulline + hydrazine
show the reaction diagram
-
-
-
?
Nomega-hydroxy-L-arginine + H2O
Nomega-hydroxy-L-citrulline + NH3
show the reaction diagram
-
2.1% activity compared to L-Arg
-
-
?
Nomega-methyl-Arg + H2O
L-citrulline + methylamine
show the reaction diagram
-
-
-
?
Nomega-methyl-L-arginine + H2O
L-citrulline + methylamine
show the reaction diagram
-
-
-
?
protein L-Arg + H2O
protein L-citrulline + NH3
show the reaction diagram
additional information
?
-