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3.5.3.13: formimidoylglutamate deiminase

This is an abbreviated version!
For detailed information about formimidoylglutamate deiminase, go to the full flat file.

Word Map on EC 3.5.3.13

Reaction

N-formimidoyl-L-glutamate
+
H2O
=
N-formyl-L-glutamate
+
NH3

Synonyms

FIG iminohydrolase, FIGLU-iminohydrolase, FIGLUase, formiminoglutamate deiminase, formiminoglutamate iminohydrolase, formiminoglutamic iminohydrolase, HutF, N-formimino-L-glutamate deiminase, N-formimino-L-glutamate iminohydrolase, Pa5106

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.3 In linear amidines
                3.5.3.13 formimidoylglutamate deiminase

Inhibitors

Inhibitors on EC 3.5.3.13 - formimidoylglutamate deiminase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
dipicolinate
-
zinc can be removed by dialysis against the metal chelator dipicolinate with the complete loss of catalytic activity
N-formimino-L-aspartate
N-guanidino-L-glutamate
-
-
N-guanidino-L-glutaric acid
-
Tetranitromethane
-
98% inhibition
additional information
-
no inhibition by N-acetyl-L-glutamate, N-carbamoyl-L-glutamate, N-formyl-L-glutamate, N-formimino-alpha-aminobutyric acid and N-formimino-gamma-aminobutyric acid at concentrations up to 10 mM
-