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3.5.3.13: formimidoylglutamate deiminase

This is an abbreviated version!
For detailed information about formimidoylglutamate deiminase, go to the full flat file.

Word Map on EC 3.5.3.13

Reaction

N-formimidoyl-L-glutamate
+
H2O
=
N-formyl-L-glutamate
+
NH3

Synonyms

FIG iminohydrolase, FIGLU-iminohydrolase, FIGLUase, formiminoglutamate deiminase, formiminoglutamate iminohydrolase, formiminoglutamic iminohydrolase, HutF, N-formimino-L-glutamate deiminase, N-formimino-L-glutamate iminohydrolase, Pa5106

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.3 In linear amidines
                3.5.3.13 formimidoylglutamate deiminase

Engineering

Engineering on EC 3.5.3.13 - formimidoylglutamate deiminase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
E235A
-
lower activity compared to the wild type enzyme
E235Q
-
lower activity compared to the wild type enzyme
H269A
-
about 5fold lower activity compared to the wild type enzyme
H269C
-
about 5fold lower activity compared to the wild type enzyme
H269N
-
about 5fold lower activity compared to the wild type enzyme