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3.5.2.9: 5-oxoprolinase (ATP-hydrolysing)

This is an abbreviated version!
For detailed information about 5-oxoprolinase (ATP-hydrolysing), go to the full flat file.

Word Map on EC 3.5.2.9

Reaction

ATP
+
5-oxo-L-proline
+ 2 H2O =
ADP
+
phosphate
+
L-glutamate

Synonyms

5-OPase, 5-oxo-L-prolinase, 5-oxoprolinase, 5OPase, ATP-dependent 5-oxoprolinase, FgOXP1, FgOXP2, FGSG_04902, FGSG_10203, L-pyroglutamate hydrolase, OPase, oplA, OPLAH, oxoprolinase, OXP1, PA4511, prokaryotic 5-oxoprolinase, PxpA, pxpA3, pxpB, pxpC, pyroglutamase, pyroglutamase (ATP-hydrolysing), pyroglutamate hydrolase, pyroglutamic hydrolase, SSO1667

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.2 In cyclic amides
                3.5.2.9 5-oxoprolinase (ATP-hydrolysing)

Inhibitors

Inhibitors on EC 3.5.2.9 - 5-oxoprolinase (ATP-hydrolysing)

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
3-methyl-5-oxo-L-proline
-
-
5-oxo-L-proline
-
inhibition of IPTase activity
DL-cis-2-oxo-5-methyloxazolidine-4-carboxylate
-
inhibition of IPTase activity
DTNB
-
could be reactivated with dithiothreitol
imidazolone carboxylate
-
-
iodoacetamide
L-2-imidazolidone-4-carboxylate
L-2-iminothiazolidine-4-carboxylate
-
inhibition of IPTase activity
L-2-oxooxazolidine-4-carboxylate
-
inhibition of IPTase activity
L-2-Oxothiazolidine-4-carboxylate
L-dihydroorotic acid
L-glutamine
-
inhibition of enzyme activity in tumor tissue
L-trans-2-oxo-5-methyloxazolidine-4-carboxylate
-
inhibition of glutamate formation; inhibition of IPTase activity
N-bromosuccinimide
-
-
N-ethylmaleimide
p-hydroxymercuribenzoate