3.5.2.9: 5-oxoprolinase (ATP-hydrolysing)

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For detailed information about 5-oxoprolinase (ATP-hydrolysing), go to the full flat file.

Word Map on EC 3.5.2.9

3.5.2.9

5-oxoproline

gamma-glutamyl

5-oxoprolinuria

l-2-oxothiazolidine-4-carboxylate

medicine

cyclotransferase

decyclization

gamma-glutamyl-cysteine

atp-hydrolyzing

meister

Reaction

+ 2 H2O =

Synonyms

5-OPase, 5-oxo-L-prolinase, 5-oxoprolinase, 5OPase, ATP-dependent 5-oxoprolinase, FgOXP1, FgOXP2, FGSG_04902, FGSG_10203, L-pyroglutamate hydrolase, OPase, oplA, OPLAH, oxoprolinase, OXP1, PA4511, prokaryotic 5-oxoprolinase, PxpA, pxpA3, pxpB, pxpC, pyroglutamase, pyroglutamase (ATP-hydrolysing), pyroglutamate hydrolase, pyroglutamic hydrolase, SSO1667

ECTree

3 Hydrolases

3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

3.5.2 In cyclic amides

3.5.2.9 5-oxoprolinase (ATP-hydrolysing)

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Results	in table
4	Activating Compound
20501	AA Sequence
11	Application
1	CAS Registry Number
8	Cloned(Commentary)
6	Cofactor
1	Crystallization (Commentary)
126	Disease/ Diagnostics
74	General Information
5	General Stability
47	Inhibitors
56	KM Value [mM]
11	Localization
34	Metals/Ions
33	Molecular Weight [Da]
88	Natural Substrates/ Products (Substrates)
431	Organism
6	Pathway
16	pH Optimum
2	pH Range
1	pH Stability
13	Protein Variants
22	Purification (Commentary)
1	Reaction
2	Reaction Type
101	Reference
147	Source Tissue
25	Specific Activity [micromol/min/mg]
8	Storage Stability
206	Substrates and Products (Substrate)
24	Subunits
95	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Temperature Stability [°C]
1	Turnover Number [1/s]

General Stability

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General Stability on EC 3.5.2.9 - 5-oxoprolinase (ATP-hydrolysing)

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the activity of PxpABC is highly unstable

Bacillus subtilis

P42963; P60495; Q7WY77

757181

unstable in absence of 5-oxo-L-proline

2 entries