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BRENDA support Phthalyl amidase

This is an abbreviated version!
For detailed information about Phthalyl amidase, go to the full flat file.


A phthalylamide
Phthalic acid
a substituted amine


Amidase, phthalyl, o-Phthalyl amidase


     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
       Phthalyl amidase

Systematic Name

Systematic Name on EC - Phthalyl amidase

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IUBMB Comments
Phthalyl-amide amidohydrolase
In the entry, "phthalyl" is used to mean "2-carboxybenzoyl". The enzyme from Xanthobacter agilis hydrolyses phthalylated amino acids, peptides, beta-lactams, aromatic and aliphatic amines. The substituent on nitrogen may be an alkyl group, but may also be complex, giving an amino acid or peptide derivative. Substitutions on the phthalyl ring include 6-F, 6-NH2, 3-OH, and a nitrogen in the aromatic ring ortho to the carboxy group attached to the amine. No cofactors are required