3.5.1.79: Phthalyl amidase

This is an abbreviated version!
For detailed information about Phthalyl amidase, go to the full flat file.

Reaction

A phthalylamide
+
H2O
=
Phthalic acid
+
a substituted amine

Synonyms

Amidase, phthalyl, o-Phthalyl amidase

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.79 Phthalyl amidase

Reference

Reference on EC 3.5.1.79 - Phthalyl amidase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Black, T.D.; Briggs, B.S.; Evans, R.; Muth, W.L.; Vangala, S.; Zmijewski, M.J.
o-Phthalyl amidase in the synthesis of loracarbef: process development using this novel biocatalyst
Biotechnol. Lett.
18
875-880
1996
Xanthobacter agilis
-
Manually annotated by BRENDA team
Costello, C.A.; Kreuzman, A.J.; Zmijewski, M.J.
Selective deprotection of phthalyl protected amines
Tetrahedron Lett.
37
7469-7472
1996
Xanthobacter agilis
-
Manually annotated by BRENDA team
Briggs, B.S.; Kreuzman, A.J.; Whitesitt, C.; Yeh, W.K.; Zmijewski, M.
Discovery, purification, and properties of o-phthalyl amidase from Xanthobacter agilis
J. Mol. Catal. , B Enzym.
2
53-69
1996
Xanthobacter agilis
-
Manually annotated by BRENDA team
Briggs, B.S.; Zmijewski Jr., M.J.
Enzyme from microbial sources: phthalyl amidase
United States Patent 5,445,959
1995
Xanthobacter agilis
-
Manually annotated by BRENDA team
Queener, S.W.; Zock, J.M.
Genes encoding and method of expressing a novel enzyme phthalyl amidase
United States Patent 5,543,497
1996
Xanthobacter agilis
-
Manually annotated by BRENDA team