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3.5.1.75: urethanase

This is an abbreviated version!
For detailed information about urethanase, go to the full flat file.

Word Map on EC 3.5.1.75

Reaction

urethane
+
H2O
=
ethanol
 +
CO2
 +
NH3

Synonyms

hydrolase, urethane, More, UreC, urethane hydrolase, urethane-hydrolyzing enzyme

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.75 urethanase

Inhibitors

Inhibitors on EC 3.5.1.75 - urethanase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1,10-phenanthroline
-
strong inhibition
4-chloromercuribenzoate
-
37% inhibition at 1 mM
Ag+
-
1 mM: complete inhibition
bathophenanthroline
-
complete inhibition, activity fully restored by addition of Fe3+ at a ratio of 4 iron atoms to 1 mol inactive protein, the apoenzyme
Cd2+
-
18% inhibition at 1 mM
ethanol
-
50% inhibition at 30% v/v
F-
-
1 mM: complete inhibition
Fe2+
-
1 mM: 67% inhibition, 10 mM: complete inhibition
iodoacetamide
iodoacetic acid
-
0.1 mM: 40% inhibition
Mn2+
-
slight inhibition
N-Benzoylphosphoric triamide
-
-
O,O-Dimethyl-O-(2,2-dichlorovinyl) phosphate
-
-
O,O-Dimethyl-O-(3-methyl-4-nitrophenyl) phosphate
-
-
p-chloromercuribenzoate
-
0.1 mM: 52% inhibition
phenylmethylsulfonyl fluoride
phenylphosphorodiamide
-
-
phenylthiophosphorodiamide
-
-
phosphoramidon
-
-
PMSF
-
84% inhibition at 1 mM
Sodium laurylsulfate
-
35 mM: complete inhibition
additional information
-