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3.5.1.67: 4-methyleneglutaminase

This is an abbreviated version!
For detailed information about 4-methyleneglutaminase, go to the full flat file.

Word Map on EC 3.5.1.67

Reaction

4-methylene-L-glutamine
+
H2O
=
4-methylene-L-glutamate
 +
NH3

Synonyms

4-methyleneglutamine amidohydrolase, 4-methyleneglutamine deamidase, amidase, 4-methyleneglutamine, MeGln amidohydrolase

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.67 4-methyleneglutaminase

Inhibitors

Inhibitors on EC 3.5.1.67 - 4-methyleneglutaminase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
4-methylene-L-glutamate
4-methylene-L-glutamine
-
competitive, glutamine as substrate, Ki: 30 mM
albizziine
arsenate
BO33-
D-glutamine
-
20 mM: 20% inhibition
diazo-oxo-norleucine
-
very slight inhibition, 4 mM: 7% inhibition
I-
-
slight inhibition
L-asparagine
-
very slight inhibition, 20 mM: 3% inhibition
L-glutamate
-
non-competitive, Ki: 5.4 mM
L-Glutamate-5-ethyl ester
-
20 mM: 40% inhibition
L-glutamate-5-hydroxamate
-
competitive, 20 mM: 35% inhibition, 4-methylene-L-glutamine as substrate
L-glutamate-5-methyl ester
-
20 mM: 63% inhibition
L-glutamate-diethyl ester
-
20 mM: 40% inhibition
L-glutamine
-
competitive, 20 mM: 50% inhibition, 4-methylene-L-glutamine as substrate
L-N5-Ethylglutamine
-
theanine, slight inhibition, 20 mM: 14% inhibition
N-acetyl-L-glutamate
-
20 mM: 78% inhibition
N-acetyl-L-glutamine
-
20 mM: 29% inhibition
NaBr
-
slight inhibition
NaCl
-
slight inhibition
NaCN
-
very slight inhibition
NaI
-
slight inhibition
Phenol red
-
competitive, Ki: 3.8 mM
S-Carbamoyl-L-cysteine
-
20 mM: 78% inhibition
Urea
-
slight inhibition, 10 mM: 10% inhibition
additional information
-