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3.5.1.5: urease

This is an abbreviated version!
For detailed information about urease, go to the full flat file.

Word Map on EC 3.5.1.5

Reaction

Urea
+
H2O
=
CO2
 + 2 NH3

Synonyms

acid urease, Arthritogenic cationic 19 kDa antigen, BPU, canatoxin, embryo-specific soybean urease, Eu1, Eu4, HPU, jack bean urease, JBU, JBURE-II, More, PMU, urea amido hydrolase, Urea amidohydrolase, urease, urease JBURE-IIb, UreC

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.5 urease

IC50 Value

IC50 Value on EC 3.5.1.5 - urease

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.4351
(+)-costunolide
Canavalia ensiformis
30°C, pH 6.8
0.1
(2-[[(2-[[2-(hydroxy-kappaO)ethyl]amino-kappaN]ethyl)imino-kappaN]methyl]-4-nitrophenolato-kappaO)(methoxymethanolato-kappaO)zinc
Canavalia ensiformis
-
value above 0.1, pH and temperature not specified in the publication
0.0224
(2-[[(2-[[2-(hydroxy-kappaO)ethyl]amino-kappaN]ethyl)imino-kappaN]methyl]-4-nitrophenolato-kappaO)(nitrato-kappaO)copper
Canavalia ensiformis
-
pH and temperature not specified in the publication
0.03251
(2E)-3-(1,3-benzodioxol-5-yl)-1-(2-hydroxyphenyl)prop-2-en-1-one
Canavalia ensiformis
-
-
0.0368
(2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol
Canavalia ensiformis
30°C, pH 6.8
1.1
(aminomethyl)methylphosphinic acid
Sporosarcina pasteurii
-
pH 7.0, 37°C
0.432 - 0.7
(aminomethyl)phosphonic acid
0.000457
(E)-1-((E)-3-phenylallylidene)thiosemicarbazide
Canavalia ensiformis
-
pH 8.2, 37°C
0.000215
(E)-1-(2-chlorobenzylidene)thiosemicarbazide
Canavalia ensiformis
-
pH 8.2, 37°C
0.000989
(E)-1-(3,4,5-trimethoxybenzylidene)thiosemicarbazide
Canavalia ensiformis
-
pH 8.2, 37°C
0.000767
(E)-1-(3-bromobenzylidene)thiosemicarbazide
Canavalia ensiformis
-
pH 8.2, 37°C
0.00067
(E)-1-(3-chlorobenzylidene)thiosemicarbazide
Canavalia ensiformis
-
pH 8.2, 37°C
0.000177
(E)-1-(3-methoxybenzylidene)thiosemicarbazide
Canavalia ensiformis
-
pH 8.2, 37°C
0.000102
(E)-1-(3-nitrobenzylidene)thiosemicarbazide
Canavalia ensiformis
-
pH 8.2, 37°C
0.000127
(E)-1-(4-(N,N-dimethylamino)benzylidene)thiosemicarbazide
Canavalia ensiformis
-
pH 8.2, 37°C
0.000707
(E)-1-(4-bromobenzylidene)thiosemicarbazide
Canavalia ensiformis
-
pH 8.2, 37°C
0.00041
(E)-1-(4-chlorobenzylidene)thiosemicarbazide
Canavalia ensiformis
-
pH 8.2, 37°C
0.000887
(E)-1-(4-methoxybenzylidene)thiosemicarbazide
Canavalia ensiformis
-
pH 8.2, 37°C
0.000547
(E)-1-(4-nitrobenzylidene)thiosemicarbazide
Canavalia ensiformis
-
pH 8.2, 37°C
0.000746
(E)-2-((E)-but-2-enylidene)hydrazinecarbothioamide
Canavalia ensiformis
-
pH 8.2, 37°C
0.00022
(E)-2-(2,3-dihydroxybenzylidene)hydrazinecarbothioamide
Canavalia ensiformis
-
pH 8.2, 37°C
0.000263
(E)-2-(2-(benzyloxy)benzylidene)hydrazinecarbothioamide
Canavalia ensiformis
-
pH 8.2, 37°C
0.00033
(E)-2-(3-(benzyloxy)-4-methoxybenzylidene)hydrazinecarbothioamide
Canavalia ensiformis
-
pH 8.2, 37°C
0.000233
(E)-2-(4-hydroxy-3,5-dimethoxybenzylidene)hydrazinecarbothioamide
Canavalia ensiformis
-
pH 8.2, 37°C
0.000682
(E)-2-(4-hydroxybenzylidene)hydrazinecarbothioamide
Canavalia ensiformis
-
pH 8.2, 37°C
0.002 - 0.003
(Hg2)2+
Canavalia ensiformis
-
-
0.112 - 0.158
([[(benzyloxy)carbonyl]amino]methyl)methylphosphinothioic O-acid
0.03
1,4-Naphthoquinone
Canavalia ensiformis
-
pH 7.7, temperature not provided
0.0243
1-(2,4-difluorophenyl)-3-phenylthiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.02993
1-(2,5-dimethoxyphenyl)-3-phenylthiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.022
1-(2-chlorophenyl)-3-(3-chlorophenyl)thiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.03703
1-(3,5-dichloropyridin-2-yl)-3-phenylthiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.0183
1-(3-bromophenyl)-3-phenylthiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.0271
1-(3-chlorophenyl)-3-(2,3-dichlorophenyl)thiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.0422
1-(3-chlorophenyl)-3-(2,4-dichlorophenyl)thiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.0241
1-(3-chlorophenyl)-3-(2,4-dimethylphenyl)thiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.0209
1-(3-chlorophenyl)-3-(2,5-dimethylphenyl)thiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.04096
1-(3-chlorophenyl)-3-(2,6-dichlorophenyl)thiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.0274
1-(3-chlorophenyl)-3-(2,6-dimethylphenyl)thiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.02006
1-(3-chlorophenyl)-3-(2-methoxyphenyl)thiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.01103
1-(3-chlorophenyl)-3-(3,4-dichlorophenyl)thiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.0163
1-(3-chlorophenyl)-3-(3,4-difluorophenyl)thiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.02446
1-(3-chlorophenyl)-3-(3-methoxyphenyl)thiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.0159
1-(3-chlorophenyl)-3-(3-methylpyridin-2-yl)thiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.02033
1-(3-chlorophenyl)-3-(4-chlorophenyl)thiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.0191
1-(3-chlorophenyl)-3-(4-fluorophenyl)thiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.02956
1-(3-chlorophenyl)-3-(4-methoxyphenyl)thiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.01503
1-(3-chlorophenyl)-3-(m-tolyl)thiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.0344
1-(3-chlorophenyl)-3-(o-tolyl)thiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.0186
1-(3-chlorophenyl)-3-(p-tolyl)thiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.02446
1-(3-chlorophenyl)-3-(pyridin-3-yl)thiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.02303
1-(3-chlorophenyl)-3-(pyridin-3-ylmethyl)thiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.0227
1-(3-chlorophenyl)-3-(pyridin-4-ylmethyl)thiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.0253
1-(3-methylpyridin-2-yl)-3-phenylthiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.03426
1-(4-bromophenyl)-3-phenylthiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.0827
1-(5-bromo-6-methylpyridin-2-yl)-3-phenylthiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.0201
1-(5-chloro-2-methylphenyl)-3-(3-chlorophenyl)thiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.03236
1-(furan-2-ylmethyl)-3-phenylthiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.02336
1-phenyl-3-(pyridin-2-yl)thiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.00843
1-phenyl-3-(pyridin-3-yl)thiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.0335
1-phenyl-3-(pyridin-3-ylmethyl)thiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.04393
1-phenyl-3-(pyridin-4-yl)thiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.0326
1-phenyl-3-(pyridin-4-ylmethyl)thiourea
Canavalia ensiformis
-
pH 6.8, 30°C
0.101
12-hydroxytetradecanoic acid
Helicobacter pylori
-
pH and temperature not specified in the publication
0.0126
2',4',5',7-tetramethoxyisoflavone
Helicobacter pylori
-
pH 8.2, 30°C
0.125 - 0.133
2,2'-bi-1,3,4-oxadiazole-5,5'(4H,4'H)-dithione
0.5
2,2'-bi-1,3,4-thiadiazole-5,5'(4H,4'H)-dithione
Proteus mirabilis
-
pH 8.2, IC50: 0.5 mM
0.18
2,2'-thenoin
Canavalia ensiformis
-
IC50: 0.18 mM
0.00197
2,3-dichloro-N'-(2,3-dichlorobenzoyl)benzohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.00266
2,3-dichloro-N'-(3,5-dichlorobenzoyl)benzohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.00272
2,3-dichloro-N'-(3,5-dimethylbenzoyl)benzohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.00735
2,3-dichloro-N'-(3-chlorobenzoyl)benzohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.138
2,4,6-trihydroxy-9H-xanthen-9-one
Canavalia ensiformis
-
pH 6.8, 30°C
0.00501
2,4-dichloro-N'-(2,4-dichlorobenzoyl)benzohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.00465
2,4-dichloro-N'-(3,5-dichlorobenzoyl)benzohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.02631
2,4-diphenyl-2,3-dihydro-1,5-benzothiazepine
Canavalia ensiformis
-
-
0.02465
2-(4-methylphenyl)-4-phenyl-2,3-dihydro-1,5-benzothiazepine
Canavalia ensiformis
-
-
0.03671
2-(4-nitrophenyl)-4-phenyl-2,3-dihydro-1,5-benzothiazepine
Canavalia ensiformis
-
-
0.019
2-chloro-N'-(3-chlorobenzoyl)-4-methylbenzohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.47
2-hydroxy-1-phenylethanone
Canavalia ensiformis
-
IC50: 0.47 mM
0.0137
2-iodo-N'-(3-methylbenzoyl)benzohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.0252
2-thioxo-5-(2,3,4-trihydroxybenzylidene)dihydro-4,6(1H,5H)-pyrimidinedione
Sporosarcina pasteurii
-
pH not specified in the publication, 30°C
0.09374
2-[(2S,4R)-2-(4-fluorophenyl)-2,3,4,5-tetrahydro-1,5-benzothiazepin-4-yl]phenol
Canavalia ensiformis
-
-
0.09121
2-[(2S,4R)-2-phenyl-2,3,4,5-tetrahydro-1,5-benzothiazepin-4-yl]phenol
Canavalia ensiformis
-
-
0.01907
2-[2-(1,3-benzodioxol-5-yl)-2,3-dihydro-1,5-benzothiazepin-4-yl]phenol
Canavalia ensiformis
-
-
0.227
2-[2-(3,4-dimethoxyphenyl)ethyl]phenol
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.000235
2-[4-(2-methylpropyl)phenyl]-N-[(3-nitrophenyl)carbamothioyl]propanamide
Canavalia ensiformis
pH 8.2, 37°C, mixed-type inhibition
0.000235
2-[4-(2-methylpropyl)phenyl]-N-[(4-sulfamoylphenyl)carbamothioyl]propanamide
Canavalia ensiformis
pH 8.2, 37°C
0.07385
3,3'-(2-bromobenzylidene)-bis-(4-hydroxycoumarin)
Canavalia ensiformis
-
-
0.08453
3,3'-(2-chlorobenzylidene)-bis-(4-hydroxycoumarin)
Canavalia ensiformis
-
-
0.08181
3,3'-(2-methoxybenzylidene)-bis-(4-hydroxycoumarin)
Canavalia ensiformis
-
-
0.05218
3,3'-(2-phenylpropylidene)-bis-(4-hydroxycoumarin)
Canavalia ensiformis
-
-
0.03503
3,3'-(2-pyridyl-methylene)-bis-(4-hydroxycoumarin)
Canavalia ensiformis
-
-
0.04609
3,3'-(2-pyrolidene)-bis-(4-hydroxycoumarin)
Canavalia ensiformis
-
-
0.07293
3,3'-(3-chlorobenzylidene)-bis-(4-hydroxycoumarin)
Canavalia ensiformis
-
-
0.05906
3,3'-(3-cinnamylidene)-bis-(4-hydroxycoumarin)
Canavalia ensiformis
-
-
0.07191
3,3'-(3-hydroxybenzylidene)-bis-(4-hydroxycoumarin)
Canavalia ensiformis
-
-
0.04841
3,3'-(3-indolidene)-bis-(4-hydroxycoumarin)
Canavalia ensiformis
-
-
0.05978
3,3'-(3-methoxybenzylidene)-bis-(4-hydroxycoumarin)
Canavalia ensiformis
-
-
0.07368
3,3'-(4-hydroxybenzylidene)-bis-(4-hydroxycoumarin)
Canavalia ensiformis
-
-
0.0553
3,3'-(4-methoxybenzylidene)-bis-(4-hydroxycoumarin)
Canavalia ensiformis
-
-
0.06501
3,3'-(4-nitrobenzylidene)-bis-(4-hydroxycoumarin)
Canavalia ensiformis
-
-
0.04292
3,3'-(crotonalidene)-bis-(4-hydroxycoumarin)
Canavalia ensiformis
-
-
0.06728
3,3'-(dihydrocinnamylidene)-bis-(4-hydroxycoumarin)
Canavalia ensiformis
-
-
0.0613
3,3'-ethylidenebis-(4-hydroxycoumarin)
Canavalia ensiformis
-
-
0.01501
3,3'-methylenebis-(4-hydroxycoumarin)
Canavalia ensiformis
-
-
0.06639
3,3'-n-butylidene-bis(4-hydroxycoumarin)
Canavalia ensiformis
-
-
0.08632
3,3'-n-hexylidene-bis(4-hydroxycoumarin)
Canavalia ensiformis
-
-
0.08474
3,3'-n-pentylidene-bis(4-hydroxycoumarin)
Canavalia ensiformis
-
-
0.037
3,4,5-trihydroxy-9H-xanthen-9-one
Canavalia ensiformis
-
pH 6.8, 30°C
0.0167
3,5-dichloro-N'-(3-chlorobenzoyl)benzohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.00971
3,5-dichloro-N'-(3-methylbenzoyl)benzohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.00182
3,5-dichloro-N'-(4-chlorobenzoyl)benzohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.00087
3,5-dichloro-N'-(4-methoxybenzoyl)benzohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.00213
3,5-dichloro-N'-(4-methylbenzoyl)benzohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.000025
3,5-dimethylphenyl diamidophosphate
Canavalia ensiformis
-
-
0.0131
3-chloro-N'-(3-chlorobenzoyl)benzohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.0089
3-chloro-N'-(3-methylbenzoyl)benzohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.00915
3-chloro-N'-(3-nitrobenzoyl)benzohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.00462
3-chloro-N'-(4-methylbenzoyl)benzohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.1
3-hydroxytetradecanoic acid
Helicobacter pylori
-
pH and temperature not specified in the publication
0.00907
3-methyl-N'-(3-methylbenzoyl)benzohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.00741
3-[(4-[[5-(2-bromophenyl)-1,3,4-thiadiazol-2-yl]amino]phenyl)(4-hydroxy-2-oxo-3,4-dihydro-2H-1-benzopyran-3-yl)methyl]-4-hydroxy-2H-1-benzopyran-2-one
Helicobacter pylori
30°C, pH not specified in the publication
0.00225
3-[(4-[[5-(2-chlorophenyl)-1,3,4-thiadiazol-2-yl]amino]phenyl)(4-hydroxy-2-oxo-3,4-dihydro-2H-1-benzopyran-3-yl)methyl]-4-hydroxy-2H-1-benzopyran-2-one
Helicobacter pylori
30°C, pH not specified in the publication
0.00029
3-[(4-[[5-(2-fluorophenyl)-1,3,4-thiadiazol-2-yl]amino]phenyl)(4-hydroxy-2-oxo-3,4-dihydro-2H-1-benzopyran-3-yl)methyl]-4-hydroxy-2H-1-benzopyran-2-one
Helicobacter pylori
30°C, pH not specified in the publication
0.01585
3-[(4-[[5-(3-bromophenyl)-1,3,4-thiadiazol-2-yl]amino]phenyl)(4-hydroxy-2-oxo-3,4-dihydro-2H-1-benzopyran-3-yl)methyl]-4-hydroxy-2H-1-benzopyran-2-one
Helicobacter pylori
30°C, pH not specified in the publication
0.01406
3-[(4-[[5-(3-chlorophenyl)-1,3,4-thiadiazol-2-yl]amino]phenyl)(4-hydroxy-2-oxo-3,4-dihydro-2H-1-benzopyran-3-yl)methyl]-4-hydroxy-2H-1-benzopyran-2-one
Helicobacter pylori
30°C, pH not specified in the publication
0.00512
3-[(4-[[5-(3-fluorophenyl)-1,3,4-thiadiazol-2-yl]amino]phenyl)(4-hydroxy-2-oxo-3,4-dihydro-2H-1-benzopyran-3-yl)methyl]-4-hydroxy-2H-1-benzopyran-2-one
Helicobacter pylori
30°C, pH not specified in the publication
0.01397
3-[(4-[[5-(4-bromophenyl)-1,3,4-thiadiazol-2-yl]amino]phenyl)(4-hydroxy-2-oxo-3,4-dihydro-2H-1-benzopyran-3-yl)methyl]-4-hydroxy-2H-1-benzopyran-2-one
Helicobacter pylori
30°C, pH not specified in the publication
0.00608
3-[(4-[[5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl]amino]phenyl)(4-hydroxy-2-oxo-3,4-dihydro-2H-1-benzopyran-3-yl)methyl]-4-hydroxy-2H-1-benzopyran-2-one
Helicobacter pylori
30°C, pH not specified in the publication
0.0024
3-[(4-[[5-(4-fluorophenyl)-1,3,4-thiadiazol-2-yl]amino]phenyl)(4-hydroxy-2-oxo-3,4-dihydro-2H-1-benzopyran-3-yl)methyl]-4-hydroxy-2H-1-benzopyran-2-one
Helicobacter pylori
30°C, pH not specified in the publication
0.0254
4'-O-methylalpinumisoflavone
Helicobacter pylori
-
pH 8.2, 30°C
0.012
4'-O-methylderrone
Helicobacter pylori
-
pH 8.2, 30°C
0.011
4-(1-amino-2-(4-hydroxyphenyl)ethyl)benzene-1,2,3-triol
Helicobacter pylori
-
-
0.047
4-(1-amino-2-(4-hydroxyphenyl)ethyl)benzene-1,2-diol
Helicobacter pylori
-
-
0.086
4-(2,3-dimethylphenyl)-5-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione
Canavalia ensiformis
-
pH 6.8, 30°C
0.0194
4-(2,4-dichlorophenyl)-6-(9-methyl-9H-carbazol-3-yl)-pyrimidin-2-amine
Canavalia ensiformis
-
pH 6.8, 30°C
0.0402
4-(2,4-difluorophenyl)-6-(9-methyl-9H-carbazol-3-yl)-pyrimidin-2-amine
Canavalia ensiformis
-
pH 6.8, 30°C
0.0456
4-(2,4-dimethylphenyl)-5-(3-nitrophenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione
Canavalia ensiformis
-
pH 6.8, 30°C
0.0281
4-(2,5-dichlorophenyl)-6-(9-methyl-9H-carbazol-3-yl)-pyrimidin-2-amine
Canavalia ensiformis
-
pH 6.8, 30°C
0.0232
4-(3,4-dichlorophenyl)-6-(9-methyl-9H-carbazol-3-yl)-pyrimidin-2-amine
Canavalia ensiformis
-
pH 6.8, 30°C
0.0452
4-(3,4-difluorophenyl)-6-(9-methyl-9H-carbazol-3-yl)-pyrimidin-2-amine
Canavalia ensiformis
-
pH 6.8, 30°C
0.0307
4-(3,4-dimethoxyphenyl)-6-(9-methyl-9H-carbazol-3-yl)-pyrimidin-2-amine
Canavalia ensiformis
-
pH 6.8, 30°C
0.0837
4-(3-aminophenyl)-6-(9-methyl-9H-carbazol-3-yl)-pyrimidin-2-amine
Canavalia ensiformis
-
pH 6.8, 30°C
0.234
4-(4-benzoyl-5-thioxo-4,5-dihydro-1,3,4-thiadiazol-2-yl)phenyl benzoate
Canavalia ensiformis
-
pH 8.2, IC50: 0.234 mM
0.032
4-(4-bromophenyl)-5-[hydroxy(phenyl)methyl]-2,4-dihydro-3H-1,2,4-triazole-3-thione
Canavalia ensiformis
-
pH and temperature not specified in the publlication
0.0951
4-(4-bromophenyl)-6-(9-methyl-9H-carbazol-3-yl)-pyrimidin-2-amine
Canavalia ensiformis
-
pH 6.8, 30°C
0.0182
4-(4-chlorophenyl)-5-[hydroxy(phenyl)methyl]-2,4-dihydro-3H-1,2,4-triazole-3-thione
Canavalia ensiformis
-
pH and temperature not specified in the publlication
0.1
4-(4-chlorophenyl)-6-(9-methyl-9H-carbazol-3-yl)-pyrimidin-2-amine
Canavalia ensiformis
-
above, pH 6.8, 30°C
0.1
4-(4-fluorophenyl)-6-(9-methyl-9H-carbazol-3-yl)-pyrimidin-2-amine
Canavalia ensiformis
-
above, pH 6.8, 30°C
0.0954
4-(4-methoxyphenyl)-6-(9-methyl-9H-carbazol-3-yl)-pyrimidin-2-amine
Canavalia ensiformis
-
pH 6.8, 30°C
0.0737
4-(9-methyl-9H-carbazol-3-yl)-6-(2,4,6-trimethoxyphenyl)-pyrimidin-2-amine
Canavalia ensiformis
-
pH 6.8, 30°C
0.0872
4-(9-methyl-9H-carbazol-3-yl)-6-(4-nitrophenyl)-pyrimidin-2-amine
Canavalia ensiformis
-
pH 6.8, 30°C
0.1
4-(9-methyl-9H-carbazol-3-yl)-6-(pyridin-2-yl)-pyrimidin-2-amine
Canavalia ensiformis
-
above, pH 6.8, 30°C
0.1
4-(9-methyl-9H-carbazol-3-yl)-6-(thiophen-2-yl)-pyrimidin-2-amine
Canavalia ensiformis
-
above, pH 6.8, 30°C
0.1
4-(9-methyl-9H-carbazol-3-yl)-6-phenylpyrimidin-2-amine
Canavalia ensiformis
-
above, pH 6.8, 30°C
0.000016
4-(benzyloxy)phenyl diamidophosphate
Canavalia ensiformis
-
-
0.0167
4-(methoxymethyl)-5-methylbenzene-1,3-diol
Canavalia ensiformis
30°C, pH 6.8
0.03
4-(p-hydroxyphenethyl)pyrogallol
Helicobacter pylori
-
-
0.125
4-amino-5-(4-hydroxyphenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione
Proteus mirabilis
-
pH 8.2, IC50: below 0.125 mM
0.163
4-amino-5-pyridin-4-yl-2,4-dihydro-3H-1,2,4-triazole-3-thione
Canavalia ensiformis
-
pH 8.2, IC50: 0.163 mM
0.079
4-butylbenzene-1,2,3-triol
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.0079
4-butylbenzene-1,2-diol
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.124
4-decylbenzene-1,2,3-triol
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.168
4-dodecylbenzene-1,2,3-triol
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.034
4-ethylbenzene-1,2,3-triol
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.0049
4-ethylbenzene-1,2-diol
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.091
4-hexylbenzene-1,2,3-triol
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.0123
4-hexylbenzene-1,2-diol
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.0056
4-hydroxy-3-[(4-hydroxy-2-oxo-3,4-dihydro-2H-1-benzopyran-3-yl)(4-[[5-(2-methoxyphenyl)-1,3,4-thiadiazol-2-yl]amino]phenyl)methyl]-2H-1-benzopyran-2-one
Helicobacter pylori
30°C, pH not specified in the publication
0.01522
4-hydroxy-3-[(4-hydroxy-2-oxo-3,4-dihydro-2H-1-benzopyran-3-yl)(4-[[5-(2-methylphenyl)-1,3,4-thiadiazol-2-yl]amino]phenyl)methyl]-2H-1-benzopyran-2-one
Helicobacter pylori
30°C, pH not specified in the publication
0.0153
4-hydroxy-3-[(4-hydroxy-2-oxo-3,4-dihydro-2H-1-benzopyran-3-yl)(4-[[5-(3-methoxyphenyl)-1,3,4-thiadiazol-2-yl]amino]phenyl)methyl]-2H-1-benzopyran-2-one
Helicobacter pylori
30°C, pH not specified in the publication
0.03844
4-hydroxy-3-[(4-hydroxy-2-oxo-3,4-dihydro-2H-1-benzopyran-3-yl)(4-[[5-(3-methylphenyl)-1,3,4-thiadiazol-2-yl]amino]phenyl)methyl]-2H-1-benzopyran-2-one
Helicobacter pylori
30°C, pH not specified in the publication
0.01469
4-hydroxy-3-[(4-hydroxy-2-oxo-3,4-dihydro-2H-1-benzopyran-3-yl)(4-[[5-(3-nitrophenyl)-1,3,4-thiadiazol-2-yl]amino]phenyl)methyl]-2H-1-benzopyran-2-one
Helicobacter pylori
30°C, pH not specified in the publication
0.0105
4-hydroxy-3-[(4-hydroxy-2-oxo-3,4-dihydro-2H-1-benzopyran-3-yl)(4-[[5-(4-methoxyphenyl)-1,3,4-thiadiazol-2-yl]amino]phenyl)methyl]-2H-1-benzopyran-2-one
Helicobacter pylori
30°C, pH not specified in the publication
0.02336
4-hydroxy-3-[(4-hydroxy-2-oxo-3,4-dihydro-2H-1-benzopyran-3-yl)(4-[[5-(4-methylphenyl)-1,3,4-thiadiazol-2-yl]amino]phenyl)methyl]-2H-1-benzopyran-2-one
Helicobacter pylori
30°C, pH not specified in the publication
0.00012
4-hydroxy-3-[(4-hydroxy-2-oxo-3,4-dihydro-2H-1-benzopyran-3-yl)[4-([5-[4-(trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-yl]amino)phenyl]methyl]-2H-1-benzopyran-2-one
Helicobacter pylori
30°C, pH not specified in the publication
0.000063
4-nitrophenyl diamidophosphate
Canavalia ensiformis
-
-
0.103
4-octylbenzene-1,2,3-triol
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.058
4-octylbenzene-1,2-diol
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.25
4-tetradecylbenzene-1,2,3-triol
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.069
4-[2-(3,4-diethoxyphenyl)ethyl]benzene-1,2,3-triol
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.071
4-[2-(3,4-dimethoxyphenyl)ethyl]benzene-1,2,3-triol
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.0227
4-[2-(3,4-dimethoxyphenyl)ethyl]benzene-1,2-diol
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.204
4-[2-(3,4-dimethoxyphenyl)ethyl]phenol
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.052
4-[2-(3-bromophenyl)ethyl]benzene-1,2,3-triol
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.0169
4-[2-(3-bromophenyl)ethyl]benzene-1,2-diol
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.235
4-[2-(3-chlorophenyl)ethyl]-1,2-dimethoxybenzene
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.05
4-[2-(3-chlorophenyl)ethyl]benzene-1,2,3-triol
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.0157
4-[2-(3-chlorophenyl)ethyl]benzene-1,2-diol
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.048
4-[2-(4-bromophenyl)ethyl]benzene-1,2,3-triol
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.254
4-[2-(4-chlorophenyl)ethyl]-1,2-dimethoxybenzene
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.047
4-[2-(4-chlorophenyl)ethyl]benzene-1,2,3-triol
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.0083
4-[2-(4-chlorophenyl)ethyl]benzene-1,2-diol
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.043
4-[2-(4-fluorophenyl)ethyl]benzene-1,2,3-triol
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.0062
4-[2-(4-fluorophenyl)ethyl]benzene-1,2-diol
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.032
4-[2-(4-hydroxyphenyl)ethyl]benzene-1,2,3-triol
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.0015
4-[2-(4-hydroxyphenyl)ethyl]benzene-1,2-diol
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.1372
5-(1,4-dihydro-9-anthracenylmethylene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
Sporosarcina pasteurii
-
pH not specified in the publication, 30°C
0.125 - 0.214
5-(1-naphthyl)-1,3,4-oxadiazole-2(3H)-thione
0.1708
5-(1H-indol-3-ylmethylene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
Sporosarcina pasteurii
-
pH not specified in the publication, 30°C
0.0321
5-(2,4-dihydroxybenzylidene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
Sporosarcina pasteurii
-
pH not specified in the publication, 30°C
0.0323
5-(2-aminobenzylidene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
Sporosarcina pasteurii
-
pH not specified in the publication, 30°C
0.0473
5-(2-bromo-4,5-dimethoxybenzylidene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
Sporosarcina pasteurii
-
pH not specified in the publication, 30°C
0.3132
5-(2-chlorophenyl)-N-(2,6-dimethylphenyl)-1,3,4-thiadiazol-2-amine
Canavalia ensiformis
-
pH 6.8, 30°C
0.0192
5-(2-hydroxy-3-methoxybenzylidene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
Sporosarcina pasteurii
-
pH not specified in the publication, 30°C
0.0327
5-(2-hydroxy-5-methoxybenzylidene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
Sporosarcina pasteurii
-
pH not specified in the publication, 30°C
0.0421
5-(2-methylbenzylidene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
Sporosarcina pasteurii
-
pH not specified in the publication, 30°C
0.0215
5-(2-thienylmethylene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
Sporosarcina pasteurii
-
pH not specified in the publication, 30°C
0.00161
5-(3,4-dihydroxybenzylidene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
Sporosarcina pasteurii
-
pH not specified in the publication, 30°C
0.0143
5-(3,4-dimethoxybenzylidene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
Sporosarcina pasteurii
-
pH not specified in the publication, 30°C
0.0106
5-(3,5-dibromo-4-hydroxybenzylidene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
Sporosarcina pasteurii
-
pH not specified in the publication, 30°C
0.0503
5-(3,5-dichloro-2-hydroxybenzylidene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
Sporosarcina pasteurii
-
pH not specified in the publication, 30°C
0.4596
5-(3-chlorophenyl)-4-(2,4-dimethylphenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione
Canavalia ensiformis
-
pH 6.8, 30°C
0.357
5-(3-chlorophenyl)-4-(2,6-dimethylphenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione
Canavalia ensiformis
-
pH 6.8, 30°C
0.0228
5-(3-hydroxy-4-methoxybenzylidene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
Sporosarcina pasteurii
-
pH not specified in the publication, 30°C
0.125
5-(3-hydroxyphenyl)-1,3,4-oxadiazole-2(3H)-thione
Proteus mirabilis
-
pH 8.2, IC50: below 0.125 mM
0.0433
5-(4-bromo-2,5-dimethoxybenzylidene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
Sporosarcina pasteurii
-
pH not specified in the publication, 30°C
0.1708
5-(4-chlorophenyl)-4-(2,4-dimethylphenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione
Canavalia ensiformis
-
pH 6.8, 30°C
0.4836
5-(4-chlorophenyl)-N-(2,3-dimethylphenyl)-1,3,4-thiadiazol-2-amine
Canavalia ensiformis
-
pH 6.8, 30°C
0.2147
5-(4-chlorophenyl)-N-(2,6-dimethylphenyl)-1,3,4-thiadiazol-2-amine
Canavalia ensiformis
-
pH 6.8, 30°C
0.0294
5-(4-ethoxybenzylidene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
Sporosarcina pasteurii
-
pH not specified in the publication, 30°C
0.0465
5-(4-hydroxy-3,5-dimethoxybenzylidene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
Sporosarcina pasteurii
-
pH not specified in the publication, 30°C
0.0425
5-(4-hydroxy-3-iodo-5-methoxybenzylidene)-2-thioxodihydro-4,6(1H,5H) pyrimidinedione
Sporosarcina pasteurii
-
pH not specified in the publication, 30°C
0.5
5-(4-hydroxyphenyl)-1,3,4-oxadiazole-2(3H)-thione
Proteus mirabilis
-
pH 8.2, IC50: 0.5 mM
0.016
5-(4-pyridinylmethylene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
Sporosarcina pasteurii
-
pH not specified in the publication, 30°C
0.0067
5-(4-[[4,6-dioxo-2-thioxotetrahydro-5(2H)pyrimidinylidene]methyl]-benzylidene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
Sporosarcina pasteurii
-
pH not specified in the publication, 30°C
0.25 - 0.95
5-benzhydryl-1,3,4-oxadiazole-2(3H)-thione
0.125
5-benzhydryl-1,3,4-thiadiazole-2(3H)-thione
Proteus mirabilis
-
pH 8.2, IC50: below 0.125 mM
0.125
5-benzyl-1,3,4-oxadiazole-2(3H)-thione
Proteus mirabilis
-
pH 8.2, IC50: below 0.125 mM
0.124 - 0.125
5-cyclohexyl-1,3,4-oxadiazole-2(3H)-thione
0.025
5-hydroxy-1,4-naphthoquinone
Canavalia ensiformis
-
pH 7.7, temperature not provided
0.125
5-phenyl-1,3,4-oxadiazole-2(3H)-thione
Proteus mirabilis
-
pH 8.2, IC50: below 0.125 mM
0.25 - 0.29
5-phenyl-1,3,4-thiadiazole-2(3H)-thione
0.125 - 0.2
5-pyridin-4-yl-1,3,4-oxadiazole-2(3H)-thione
0.124 - 0.125
5-pyridin-4-yl-1,3,4-thiadiazole-2(3H)-thione
0.0214
5-[(2-hydroxy-1-naphthyl)methylene]-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
Sporosarcina pasteurii
-
pH not specified in the publication, 30°C
0.0182
5-[(5-methyl-2-furyl)methylene]-2-thioxodihydro-4,6(1H,5H)pyrimidinedione
Sporosarcina pasteurii
-
pH not specified in the publication, 30°C
0.095 - 0.5
5-[(5-thioxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)methyl]-1,3,4-oxadiazole-2(3H)-thione
0.095 - 0.5
5-[(5-thioxo-4,5-dihydro-1,3,4-thiadiazol-2-yl)methyl]-1,3,4-thiadiazole-2(3H)-thione
0.0628
5-[(6-bromo-4-chloro-2-oxo-2H-chromen-3-yl)methylene]-2-thioxodihydro 4,6(1H,5H)-pyrimidinedione
Sporosarcina pasteurii
-
pH not specified in the publication, 30°C
0.016
5-[(6-methyl-2-pyridinyl)methylene]-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
Sporosarcina pasteurii
-
pH not specified in the publication, 30°C
0.093 - 0.125
5-[3-(5-thioxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)propyl]-1,3,4-oxadiazole-2(3H)-thione
0.0585
5-[4(dimethylamino) benzylidene]-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
Sporosarcina pasteurii
-
pH not specified in the publication, 30°C
0.41 - 0.5
5-[4-(benzyloxy)phenyl]-1,3,4-oxadiazole-2(3H)-thione
0.0181
5-[4-(methylsulfanyl)benzylidene]-2-thioxodihydro-4,6(1H,5H) pyrimidinedione
Sporosarcina pasteurii
-
pH not specified in the publication, 30°C
0.244
5-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-3H-[1,3,4]oxadiazole-2-thione
Canavalia ensiformis
-
pH 8.2, IC50: 0.244 mM
0.0167
5-[hydroxy(phenyl)methyl]-4-(4-methylphenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione
Canavalia ensiformis
-
pH and temperature not specified in the publlication
0.1317
5-[hydroxy(phenyl)methyl]-4-(4-nitrophenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione
Canavalia ensiformis
-
pH and temperature not specified in the publlication
0.0256
6'-O-coumaroylaloesin
Canavalia ensiformis
30°C, pH 6.8
0.07
6-hydroxytetradecanoic acid
Helicobacter pylori
-
pH and temperature not specified in the publication
0.0111
6a,12a-dehydroxydegueline
Helicobacter pylori
-
pH 8.2, 30°C
0.01506 - 0.09367
7'-hydroxy-2,2'-dioxo-2H,2'H-6,8'-bichromen-7-yl alpha-L-mannopyranoside
0.02417 - 0.02939
7'-hydroxy-2,2'-dioxo-3'-[(2-oxo-2H-chromen-7-yl)oxy]-2H,2'H-8,8'-bichromen-7-yl alpha-D-glucopyranoside
0.03762 - 0.04
7'-methoxy-2,2'-dioxo-3'-[(2-oxo-2H-chromen-7-yl)oxy]-2H,2'H-8,8'-bichromen-7-yl alpha-D-glucopyranoside
0.14
7,8,4'-trihydroxyisoflavone
Helicobacter pylori
-
-
0.02205 - 0.0263
7-hydroxy-2,2'-dioxo-2H,2'H-6,8'-bichromen-7'-yl alpha-L-mannopyranoside
0.0079
7-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Helicobacter pylori
-
pH 8.2, 30°C
0.09
7-hydroxytetradecanoic acid
Helicobacter pylori
-
pH and temperature not specified in the publication
0.0373
7-methoxy-6'-O-coumaroylaloesin
Canavalia ensiformis
30°C, pH 6.8
0.0084
7-O-methylcuneantin
Helicobacter pylori
-
pH 8.2, 30°C
0.05527 - 0.06191
7-[(7-methoxy-2-oxo-2H-chromen-3-yl)oxy]-2-oxo-2H-chromen-6-yl alpha-D-glucopyranoside
0.02901 - 0.0316
8-hydroxy-3-[(6-hydroxy-2-oxo-2H-chromen-7-yl)oxy]-2-oxo-2H-chromen-7-yl beta-D-glucopyranoside
0.021
8-methyl-2H-pyrido[1,2-a]pyrimidine-2,4(3H)-dione
Canavalia ensiformis
pH not specified in the publication, 25°C
0.083
9-hydroxytetradecanoic acid
Helicobacter pylori
-
pH and temperature not specified in the publication
0.005 - 0.045
Acetohydroxamic acid
2.9
acetol
Canavalia ensiformis
-
IC50: 2.9 mM
0.000000023 - 0.003
Ag+
0.1149
aloe emodin
Canavalia ensiformis
30°C, pH 6.8
0.4164
aloe emodin 11-O-alpha-D-rhamnopyranoside
Canavalia ensiformis
30°C, pH 6.8
0.232
alpinumisoflavone
Helicobacter pylori
-
pH 8.2, 30°C
1.1 - 2.53
aminomethyl(P-methyl)phosphinic acid
0.0173
atalantoflavone
Helicobacter pylori
-
pH 8.2, 30°C
0.14
avicularin
Canavalia ensiformis
-
pH 6.0, 37°C
0.031
beta-(o-methoxyphenyl)-gamma,gamma-bis(8-quinolinoxy)germa-gamma-lactone
Proteus mirabilis
-
-
0.0944
Calopogonium isoflavone A
Helicobacter pylori
-
pH 8.2, 30°C
0.02425
chloro(2-[[(2-[[2-(hydroxy-kappaO)ethyl]amino-kappaN]ethyl)imino-kappaN]methyl]-4-nitrophenolato-kappaO)copper
Canavalia ensiformis
-
pH and temperature not specified in the publication
0.2
copper(II) complex [CuClL1]*CH3OH
Helicobacter pylori
-
pH 7.4, 37°C
4.06
copper(II) complex [CuClL2]*CH3OH
Helicobacter pylori
-
pH 7.4, 37°C
5.14
copper(II) complex [CuL1(NCS)]
Helicobacter pylori
-
pH 7.4, 37°C
5.52
copper(II) complex [CuL3(NCS)]*CH3OH
Helicobacter pylori
-
pH 7.4, 37°C
0.26
copper(II) complex [CuL4(NCS)]*0.4H2O
Helicobacter pylori
-
pH 7.4, 37°C
0.1
copper(II) complex [CuL5(bipy)]
Helicobacter pylori
-
pH 7.4, 37°C
0.002 - 0.0033
Cu2+
0.00051
ethyl 4-(3-benzoylthioureido) benzoate
Canavalia ensiformis
pH 8.2, 37°C
0.00028
ethyl 4-[3-(2,4-dichlorobenzoyl)thioureido]benzoate
Canavalia ensiformis
pH 8.2, 37°C
0.00035
ethyl 4-[3-(2-bromobenzoyl)thioureido]benzoate
Canavalia ensiformis
pH 8.2, 37°C
0.00073
ethyl 4-[3-(2-fluorobenzoyl)thioureido]benzoate
Canavalia ensiformis
pH 8.2, 37°C
0.00013
ethyl 4-[3-(3,4-dimethoxybenzoyl)thioureido]benzoate
Canavalia ensiformis
pH 8.2, 37°C
0.00026
ethyl 4-[3-(3-chlorobenzoyl)thioureido]benzoate
Canavalia ensiformis
pH 8.2, 37°C
0.00047
ethyl 4-[3-(3-methoxybenzoyl)thioureido]benzoate
Canavalia ensiformis
pH 8.2, 37°C
0.0017
ethyl 4-[3-(3-methylbenzoyl)thioureido]benzoate
Canavalia ensiformis
pH 8.2, 37°C
0.00021
ethyl 4-[3-(4-methoxybenzoyl)thioureido]benzoate
Canavalia ensiformis
pH 8.2, 37°C
0.00067
ethyl 4-[3-(4-methylbenzoyl)thioureido]benzoate
Canavalia ensiformis
pH 8.2, 37°C
0.0145
feralolide
Canavalia ensiformis
30°C, pH 6.8
0.0393
feroxidin
Canavalia ensiformis
30°C, pH 6.8
0.36
furoin
Canavalia ensiformis
-
IC50: 0.36 mM
0.12
guaijaverin
Canavalia ensiformis
-
pH 6.0, 37°C
0.000071 - 0.003
Hg2+
0.1
Hydroxyurea
Canavalia ensiformis
-
IC50: 0.1 mM
0.03102
hydroxy[3-(5-[4-[(4-hydroxy-2-oxo-2H-1-benzopyran-3-yl)(4-hydroxy-2-oxo-3,4-dihydro-2H-1-benzopyran-3-yl)methyl]anilino]-1,3,4-thiadiazol-2-yl)phenyl]oxoammonium
Helicobacter pylori
30°C, pH not specified in the publication
0.16
isoquercitrin
Canavalia ensiformis
-
pH 6.0, 37°C
0.014
lyciumaside
Canavalia ensiformis
30°C, pH 6.8
0.02801 - 0.03184
methyl 2-amino-4,5,6,7,8,9-hexahydrocycloocta[b]thiophene-3-carboxylate
0.00534 - 0.0093
methyl 2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
0.00083 - 0.00281
methyl 2-amino-4-methylthiophene-3-carboxylate
0.01107 - 0.01658
methyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate
0.00213 - 0.00504
methyl 2-amino-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate
0.01832 - 0.02495
methyl 2-[(methoxycarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
0.00077 - 0.00299
methyl 2-[bis(chlorocarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
0.00635 - 0.01242
methyl 2-[[(chloromethoxy)carbonyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
0.0271 - 0.02908
methyl 2-[[(chloromethoxy)carbonyl]amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate
0.01321 - 0.01945
methyl 2-[[(dichloromethoxy)carbonyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
0.01054 - 0.01369
methyl 2-[[(methylsulfanyl)carbonothioyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
0.06 - 0.884
methyl[(methylamino)methyl]phosphinic acid
0.00912
N'-(2,3-dichlorobenzoyl)-3,4,5-trimethoxybenzohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH8, 37°C, 30 min.
0.0123
N'-(2,4-dichlorobenzoyl)pyridine-3-carbohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.0084
N'-(2-bromobenzylidene)-2-(4-nitrophenoxy)acetohydrazide
Helicobacter pylori
-
23°C, pH not specified in the publication
0.0133
N'-(2-ethoxybenzoyl)pyridine-3-carbohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.0147
N'-(3-chlorobenzoyl)pyridine-3-carbohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.0105
N'-(3-methylbenzoyl)pyridine-3-carbohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.00383
N'-(4-chlorobenzoyl)pyridine-3-carbohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.00164
N'-(4-methoxybenzoyl)-3,5-dimethylbenzohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
-
0.00987
N'-(4-methylbenzoyl)pyridine-3-carbohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.0202
N'-(4-nitrobenzylidene)-2-(4-nitrophenoxy)acetohydrazide
Helicobacter pylori
-
23°C, pH not specified in the publication
0.00948
N'-benzoyl-2,3-dichlorobenzohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.0053
N'-benzoyl-2,4-dichlorobenzohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.00623 - 0.00757
N'-benzoyl-3-chlorobenzohydrazide
0.0127
N'-benzoyl-3-methylbenzohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.00932
N'-benzoyl-4-chlorobenzohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.00963
N'-benzoyl-4-methoxybenzohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.0136
N'-benzoyl-4-methylbenzohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.00678
N'-benzoylbenzohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.00964
N'-benzoylpyridine-3-carbohydrazide
Canavalia ensiformis
100 mM urea, 1 mM EDTA, 10 mM K2HPO4, 10 mM LiCl2, pH 8, 37°C, 30 min.
0.4261
N-(2,3-dimethylphenyl)-5-phenyl-1,3,4-thiadiazol-2-amine
Canavalia ensiformis
-
pH 6.8, 30°C
0.017
N-(2,4-dichlorophenyl)-N'-(3,4-dimethylphenyl)thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.01423
N-(2,4-dichlorophenyl)-N'-(3,5-dimethylphenyl)thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.01543
N-(2,4-dichlorophenyl)-N'-(4-ethylphenyl)thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.01925
N-(2,4-difluorophenyl)-N'-(2-iodophenyl)thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.01819
N-(2,4-difluorophenyl)-N'-(3,4-dimethylphenyl)thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.0133
N-(2,4-difluorophenyl)-N'-(3,5-dimethylphenyl)thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.01119
N-(2,4-difluorophenyl)-N'-(4-iodophenyl)thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.3982
N-(2,4-dimethylphenyl)-5-(3-nitrophenyl)-1,3,4-thiadiazol-2-amine
Canavalia ensiformis
-
pH 6.8, 30°C
0.01051
N-(2,5-dimethylphenyl)-N'-(3-methoxyphenyl)thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.03922
N-(2,5-dimethylphenyl)-N'-[3-(trifluoromethyl)phenyl]thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.02301
N-(2-bromophenyl)-N'-(4-ethylphenyl)thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.0397
N-(2-bromophenyl)-N'-(5-chloro-2,4-dimethoxyphenyl)thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.02223
N-(2-bromophenyl)-N'-[2-hydroperoxy-5-(trifluoromethyl)phenyl]thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.01922
N-(2-bromophenyl)-N'-[3-(methylsulfanyl)phenyl]thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.01278
N-(2-chloro-4,6-dimethoxyphenyl)-N'-(3-chlorophenyl)thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.01331
N-(2-chloro-4,6-dimethoxyphenyl)-N'-[3-(trifluoromethyl)phenyl]thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.01844
N-(2-iodophenyl)-N'-(3-methoxyphenyl)thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.00002
N-(2-methoxy-4-nitrophenyl)phosphoric triamide
Canavalia ensiformis
-
-
0.003
N-(2-nitrophenyl)phosphoric triamide
Canavalia ensiformis
-
-
0.000014
N-(2-phenylethyl)phosphoric triamide
Canavalia ensiformis
-
-
0.01386
N-(2-phenylethyl)phosphorothioic triamide
Canavalia ensiformis
-
-
0.06712
N-(3,4-dimethylphenyl)-N'-[2-(trifluoromethyl)phenyl]thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.01928
N-(3,4-dimethylphenyl)-N'-[2-hydroperoxy-5-(trifluoromethyl)phenyl]thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.01948
N-(3,4-dimethylphenyl)-N'-[3-(trifluoromethyl)phenyl]thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.01732
N-(3,5-dimethylphenyl)-N'-(3-methoxyphenyl)thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.01219
N-(3-chlorophenyl)-N'-(3-nitrophenyl)thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.01334
N-(3-chlorophenyl)-N'-[2-methoxy-5-(trifluoromethyl)phenyl]thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.01011
N-(3-methoxyphenyl)-N'-(3-nitrophenyl)thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.00557
N-(3-methoxyphenyl)phosphoric triamide
Canavalia ensiformis
-
-
0.04255
N-(3-methylpyridin-2-yl)phosphorothioic triamide
Canavalia ensiformis
-
-
0.00071
N-(3-morpholin-2-ylpropyl)phosphoric triamide
Canavalia ensiformis
-
-
0.00007
N-(3-nitropyridin-2-yl)phosphoric triamide
Canavalia ensiformis
-
-
0.01729
N-(4-bromophenyl)-N'-(2,4-difluorophenyl)thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.01712
N-(4-bromophenyl)-N'-(3-chlorophenyl)thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.01541
N-(4-bromophenyl)-N'-(3-fluorophenyl)thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.05121
N-(4-bromophenyl)-N'-(3-methoxyphenyl)thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.0698
N-(4-chlorophenyl)-N'-[2-(trifluoromethyl)phenyl]thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.04425
N-(4-cyclohexylphenyl)phosphoric triamide
Canavalia ensiformis
-
-
0.07299
N-(4-ethylphenyl)-N'-(3-methoxyphenyl)thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.06186
N-(4-ethylphenyl)-N'-[3-(trifluoromethyl)phenyl]thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.06742
N-(4-fluoro-3-nitrophenyl)-N'-(3-methoxyphenyl)thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.06033
N-(4-iodophenyl)-N'-(3-methoxyphenyl)thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.01123
N-(4-iodophenyl)-N'-[3-(trifluoromethyl)phenyl]thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.00001
N-(4-methoxy-1,3-benzothiazol-2-yl)phosphoric triamide
Canavalia ensiformis
-
-
0.00001
N-(4-methyl-1,3-benzothiazol-2-yl)phosphoric triamide
Canavalia ensiformis
-
-
0.000003
N-(4-methyl-2-nitrophenyl)phosphoric triamide
Canavalia ensiformis
-
-
0.0003
N-(4-nitrophenyl)phosphoric triamide
Canavalia ensiformis
-
-
0.01298
N-(4-phenoxyphenyl)phosphoric triamide
Canavalia ensiformis
-
-
0.01711
N-(5-chloro-2,4-dimethoxyphenyl)-N'-(3-methoxyphenyl)thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.0351
N-(5-chloro-2,4-dimethoxyphenyl)-N'-[2-(trifluoromethyl)phenyl]thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.01916
N-(5-chloro-2-methylphenyl)-N'-(3,4-dichlorophenyl)thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.000005
N-(6-ethoxy-1,3-benzothiazol-2-yl)phosphoric triamide
Canavalia ensiformis
-
-
0.000005
N-(6-fluoro-1,3-benzothiazol-2-yl)phosphoric triamide
Canavalia ensiformis
-
-
0.000212
N-(benzylcarbamothioyl)-2-[4-(2-methylpropyl)phenyl]propanamide
Canavalia ensiformis
pH 8.2, 37°C
0.0018 - 0.0031
N-(N'-benzyloxycarbonylglycyl)aminomethyl(P-methyl)phosphinothioic acid
0.000002
N-1,3-benzothiazol-2-ylphosphoric triamide
Canavalia ensiformis
-
-
0.00296
N-1,3-benzothiazol-2-ylphosphorothioic triamide
Canavalia ensiformis
-
-
0.00256
N-adamant-1-ylphosphoric triamide
Canavalia ensiformis
-
-
0.123 - 0.319
N-benzyloxycarbonylaminomethyl(P-methyl)phosphinic acid
0.06 - 0.086
N-glycyl-aminomethyl(P-methyl)phosphinic acid
0.0172
N-hydroxyacetamide
Helicobacter pylori
-
cell free urease preparation, pH not specified in the publication, temperature not specified in the publication
0.0001
N-n-butylthiophosphorictriamide
Canavalia ensiformis
-
-
0.00053
N-naphthalen-1-ylphosphoric triamide
Canavalia ensiformis
-
-
0.00363
N-phenylphosphoric triamide
Canavalia ensiformis
-
-
0.000225
N-[(2,3-dichlorophenyl)carbamothioyl]-2-[4-(2-methylpropyl)phenyl]propanamide
Canavalia ensiformis
pH 8.2, 37°C, competitive inhibition, irreversible
0.000211
N-[(2,4-dinitrophenyl)carbamothioyl]-2-[4-(2-methylpropyl)phenyl]propanamide
Canavalia ensiformis
pH 8.2, 37°C
0.00021
N-[(3,5-dinitrophenyl)carbamothioyl]-2-[4-(2-methylpropyl)phenyl]propanamide
Canavalia ensiformis
pH 8.2, 37°C
0.000209
N-[(4-bromophenyl)carbamothioyl]-2-[4-(2-methylpropyl)phenyl]propanamide
Canavalia ensiformis
pH 8.2, 37°C
0.000218
N-[(4-chlorophenyl)carbamothioyl]-2-[4-(2-methylpropyl)phenyl]propanamide
Canavalia ensiformis
pH 8.2, 37°C
0.000215
N-[(4-methoxyphenyl)carbamothioyl]-2-[4-(2-methylpropyl)phenyl]propanamide
Canavalia ensiformis
pH 8.2, 37°C
0.000048
N-[2-(4-fluorophenyl)ethyl]phosphoric triamide
Canavalia ensiformis
-
-
0.00002
N-[2-(difluoromethoxy)phenyl]phosphoric triamide
Canavalia ensiformis
-
-
0.075
N-[2-(trifluoromethoxy)phenyl]phosphoric triamide
Canavalia ensiformis
-
-
0.01513
N-[3-(methylsulfanyl)phenyl]-N'-[2-(trifluoromethyl)phenyl]thiourea
Sporosarcina pasteurii
30°C, pH 6.8
0.0035
N-[4-(benzyloxy)phenyl]phosphoric triamide
Canavalia ensiformis
-
-
0.6 - 0.754
N-[[hydroxy(methyl)phosphoryl]methyl]-L-phenylalaninamide
0.15 - 0.342
N-[[hydroxy(methyl)phosphoryl]methyl]-L-serinamide
0.485 - 0.617
N-[[hydroxy(methyl)phosphoryl]methyl]-L-valinamide
0.45 - 0.64
N2-[(benzyloxy)carbonyl]-N-[[hydroxy(methyl)phosphoryl]methyl]glycinamide
0.08 - 0.183
O-benzyl-N-[[hydroxy(methyl)phosphoryl]methyl]-L-serinamide
0.01654
O-[4-(benzyloxy)phenyl] diamidothiophosphate
Canavalia ensiformis
-
-
0.0365
oxovanadium complex [VOL(AHA)]
Helicobacter pylori
-
37°C, pH 7.4
0.0051
p-benzoquinone
Canavalia ensiformis
-
-
0.000003
phenylphosphorodiamidate
Canavalia ensiformis
-
-
0.08
quercetin
Canavalia ensiformis
-
pH 6.0, 37°C
0.19
quercetin-4'-O-beta-D-glucopyranoside
Canavalia ensiformis
-
pH 6.0, 37°C
0.2
quercitrin
Canavalia ensiformis
-
pH 6.0, 37°C
0.0209
tetracosyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
Canavalia ensiformis
-
pH 6.8, 30°C
0.01506 - 18.5
Thiourea
0.258 - 1.455
[(acetylamino)methyl]methylphosphinic acid
0.463
[(acetylamino)methyl]phosphonic acid
Sporosarcina pasteurii
-
pH 7.0, 37°C
0.256 - 1.632
[(benzylamino)methyl]methylphosphinic acid
0.0038 - 0.0144
[(dimethylamino)methyl]methylphosphinic acid
0.049 - 0.082
[(dimethylamino)methyl]phosphonic acid
0.228 - 0.678
[(methylamino)methyl]phosphonic acid
0.0161
[5-[(4-methylphenyl)amino]-1,3,4-oxadiazol-2-yl](phenyl)methanol
Canavalia ensiformis
-
pH and temperature not specified in the publlication
0.0803
[5-[(4-nitrophenyl)amino]-1,3,4-oxadiazol-2-yl](phenyl)methanol
Canavalia ensiformis
-
pH and temperature not specified in the publlication
0.3
[[benzyl(methyl)amino]methyl]phosphonic acid
Sporosarcina pasteurii
-
pH 7.0, 37°C
additional information
3,3'-(1H-indol-3-ylmethanediyl)bis(4-hydroxy-2H-chromen-2-one)