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3.5.1.49: formamidase

This is an abbreviated version!
For detailed information about formamidase, go to the full flat file.

Word Map on EC 3.5.1.49

Reaction

Formamide
+
H2O
=
formate
+
NH3

Synonyms

acetamidase/formamidase, Amds/fmds, AmiF, AmiF formamidase, BceAmiF, Fmd, formamidase, formamidase AmiF, Formamide amidohydrolase, formamide aminohydrolase, HpyAmiF, TE19

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.49 formamidase

Inhibitors

Inhibitors on EC 3.5.1.49 - formamidase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Hg2+
-
complete inhibition at concentrations above 15 mM
iodoacetamide
-
complete inhibition at concentrations above 15 mM
iodoacetate
-
2.5 mM, 55% inhibition
Thiourea
-
competitive inhibition, Ki: 4.6 mM
Urea
inhibition kinetics and effects on enzyme structure, overview
additional information
-
the presence of EDTA and dithiothreitol has no significant effect on enzyme activity
-