3.5.1.46: 6-aminohexanoate-oligomer exohydrolase

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For detailed information about 6-aminohexanoate-oligomer exohydrolase, go to the full flat file.

Word Map on EC 3.5.1.46

3.5.1.46

flavobacterium

arthrobacter

nylon-6

amide

beta-lactamase

carboxylesterase

esterase

esterolytic

hydrolases

vapour-diffusion

tetrahedral

penicillin-recognizing

man-made

sitting-drop

compendium

Reaction

= 2 6-aminohexanoate

Synonyms

6-aminohexanoic acid oligomer hydrolase, EII, EII', Nylon oligomers degrading enzyme EII, Nylon oligomers degrading enzyme EII', nylon oligomer hydrolase, 6-aminohexanoate oligomer hydrolase, NylCA, NylCK, NylCP2, Hyb-24DN, nylon-oligomer degrading enzyme, NylB, 6-aminohexanoate-dimer hydrolase, N-(6-aminohexanoyl)-6-aminohexanoate amidohydrolase, 6-aminohexanoate dimer hydrolase, Ahx dimer hydrolase, Hyb-24

ECTree

3 Hydrolases

3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

3.5.1 In linear amides

3.5.1.46 6-aminohexanoate-oligomer exohydrolase

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Systematic Name on EC 3.5.1.46 - 6-aminohexanoate-oligomer exohydrolase

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N-(6-aminohexanoyl)-6-aminohexanoate exoamidohydrolase

The enzyme is involved in degradation of nylon-6 oligomers. It degrades linear oligomers of 6-aminohexanoate with a degree of polymerization of 2--20 by exo-type cleavage, removing residues sequentially from the N-terminus. Activity decreases with the increase of the polymerization number of the oligomer. cf. EC 3.5.1.117, 6-aminohexanoate-oligomer endohydrolase and EC 3.5.2.12, 6-aminohexanoate-cyclic-dimer hydrolase.