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3.5.1.46: 6-aminohexanoate-oligomer exohydrolase

This is an abbreviated version!
For detailed information about 6-aminohexanoate-oligomer exohydrolase, go to the full flat file.

Word Map on EC 3.5.1.46

Reaction

N-(6-aminohexanoyl)-6-aminohexanoate
+
H2O
= 2 6-aminohexanoate

Synonyms

6-aminohexanoate dimer hydrolase, 6-aminohexanoate oligomer hydrolase, 6-aminohexanoate-dimer hydrolase, 6-aminohexanoic acid oligomer hydrolase, Ahx dimer hydrolase, EII, EII', Hyb-24, Hyb-24DN, N-(6-aminohexanoyl)-6-aminohexanoate amidohydrolase, NylB, NylCA, NylCK, NylCP2, nylon oligomer hydrolase, Nylon oligomers degrading enzyme EII, Nylon oligomers degrading enzyme EII', nylon-oligomer degrading enzyme

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.46 6-aminohexanoate-oligomer exohydrolase

Reference

Reference on EC 3.5.1.46 - 6-aminohexanoate-oligomer exohydrolase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Kanagawa, K.; Oishi, M.; Negoro, S.; Urabe, I.; Okada, H.
Characterization of the 6-aminohexanoate-dimer hydrolase from Pseudomonas sp. NK87
J. Gen. Microbiol.
139
787-795
1993
Flavobacterium sp., Pseudomonas sp., Flavobacterium sp. KI72, Pseudomonas sp. NK87
Manually annotated by BRENDA team
Fujiyama, K.; Zhang, Y.Z.; Negoro, S.; Urabe, I.; Okada, H.
Characterization of hybrid enzymes between 6-aminohexanoate-dimer hydrolase and its analogues protein
J. Ferment. Bioeng.
71
298-302
1991
Flavobacterium sp., Flavobacterium sp. KI72
-
Manually annotated by BRENDA team
Hatanaka, H.S.; Fujiyama, K.; Negoro, S.; Urabe, I.; Okada, H.
Alteration of catalytic function of 6-aminohexanoate-dimer hydrolase by site-directed mutagenesis
J. Ferment. Bioeng.
71
191-193
1991
Flavobacterium sp., Flavobacterium sp. KI72
-
Manually annotated by BRENDA team
Kinoshita, S.
Microbial degradation of 6-aminohexanoic acid cyclic dimer and its enzymes
Hakko Kogaku Kaishi
60
363-375
1982
Flavobacterium sp., Flavobacterium sp. KI72
-
Manually annotated by BRENDA team
Kinoshita, S.; Terada, T.; Taniguchi, T.; Takene, Y.; Masuda, S.
Purification and characterization of 6-aminohexanoic acid-oligomer hydrolase of Flavobacterium sp. KI72
Eur. J. Biochem.
116
547-551
1981
Flavobacterium sp., Flavobacterium sp. KI72
Manually annotated by BRENDA team
Ohki, T.; Mizuno, N.; Shibata, N.; Takeo, M.; Negoro, S.; Higuchi, Y.
Crystallization and X-ray diffraction analysis of 6-aminohexanoate-dimer hydrolase from Arthrobacter sp. KI72
Acta Crystallogr. Sect. F
61
928-930
2005
Arthrobacter sp.
Manually annotated by BRENDA team
Ohki, T.; Wakitani, Y.; Takeo, M.; Yasuhira, K.; Shibata, N.; Higuchi, Y.; Negoro, S.
Mutational analysis of 6-aminohexanoate-dimer hydrolase: relationship between nylon oligomer hydrolytic and esterolytic activities
FEBS Lett.
580
5054-5058
2006
Arthrobacter sp.
Manually annotated by BRENDA team
Negoro, S.; Ohki, T.; Shibata, N.; Mizuno, N.; Wakitani, Y.; Tsurukame, J.; Matsumoto, K.; Kawamoto, I.; Takeo, M.; Higuchi, Y.
X-ray crystallographic analysis of 6-aminohexanoate-dimer hydrolase: molecular basis for the birth of a nylon oligomer-degrading enzyme
J. Biol. Chem.
280
39644-39652
2005
Arthrobacter sp.
Manually annotated by BRENDA team
Yasuhira, K.; Tanaka, Y.; Shibata, H.; Kawashima, Y.; Ohara, A.; Kato, D.; Takeo, M.; Negoro, S.
6-Aminohexanoate oligomer hydrolases from the alkalophilic bacteria Agromyces sp. strain KY5R and Kocuria sp. strain KY2
Appl. Environ. Microbiol.
73
7099-7102
2007
Arthrobacter sp., Agromyces sp., Kocuria sp., Kocuria sp. KY2, Agromyces sp. KY5R
Manually annotated by BRENDA team
Negoro, S.; Ohki, T.; Shibata, N.; Sasa, K.; Hayashi, H.; Nakano, H.; Yasuhira, K.; Kato, D.; Takeo, M.; Higuchi, Y.
Nylon-oligomer degrading enzyme/substrate complex: catalytic mechanism of 6-aminohexanoate-dimer hydrolase
J. Mol. Biol.
370
142-156
2007
Flavobacterium sp. (P07062)
Manually annotated by BRENDA team
Taguchi, H.; Wakamatsu, M.; Aso, K.; Ono, S.; Shin, T.; Akamatsu, T.
A simple assay for 6-aminohexanoate-oligomer-hydrolase using N-(4-nitrophenyl)-6-aminohexanamide
J. Biosci. Bioeng.
114
586-588
2012
Arthrobacter sp., Pseudomonas sp., Pseudomonas sp. NK87, Arthrobacter sp. KI72
Manually annotated by BRENDA team
akehara, I.; Fujii, T.; Tanimoto, Y.; Kato, D.I.; Takeo, M.; Negoro, S.
Metabolic pathway of 6-aminohexanoate in the nylon oligomer-degrading bacterium Arthrobacter sp. KI72 identification of the enzymes responsible for the conversion of 6-aminohexanoate to adipate
Appl. Microbiol. Biotechnol.
102
801-814
2018
Paenarthrobacter ureafaciens (P07061)
Manually annotated by BRENDA team
Negoro, S.; Kawashima, Y.; Shibata, N.; Kobayashi, T.; Baba, T.; Lee, Y.H.; Kamiya, K.; Shigeta, Y.; Nagai, K.; Takehara, I.; Kato, D.; Takeo, M.; Higuchi, Y.
Mutations affecting the internal equilibrium of the reaction catalyzed by 6-aminohexanoate-dimer hydrolase
FEBS Lett.
590
3133-3143
2016
Paenarthrobacter ureafaciens (P07061)
Manually annotated by BRENDA team
Ando, H.; Shigeta, Y.; Baba, T.; Watanabe, C.; Okiyama, Y.; Mochizuki, Y.; Nakano, M.
Hydration effects on enzyme-substrate complex of nylon oligomer hydrolase inter-fragment interaction energy study by the fragment molecular orbital method
Mol. Phys.
113
319-326
2015
Paenarthrobacter ureafaciens (P07061)
-
Manually annotated by BRENDA team