3.5.1.36: N-methyl-2-oxoglutaramate hydrolase

This is an abbreviated version!
For detailed information about N-methyl-2-oxoglutaramate hydrolase, go to the full flat file.

Reaction

N-Methyl-2-oxoglutaramate
+
H2O
=
2-oxoglutarate
+
methylamine

Synonyms

5-hydroxy-N-methylpyroglutamate synthase, 5-hydroxy-N-methylpyroglutamate synthetase

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.36 N-methyl-2-oxoglutaramate hydrolase

Systematic Name

Systematic Name on EC 3.5.1.36 - N-methyl-2-oxoglutaramate hydrolase

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SYSTEMATIC NAME
IUBMB Comments
N-methyl-2-oxoglutaramate methylamidohydrolase
In the reverse reaction, the product cyclizes non-enzymically to 2-hydroxy-N-methyl-5-oxo-L-proline.