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3.5.1.24: choloylglycine hydrolase

This is an abbreviated version!
For detailed information about choloylglycine hydrolase, go to the full flat file.

Word Map on EC 3.5.1.24

Reaction

glycocholate
+
H2O
=
cholate
 +
glycine

Synonyms

BAH1, BFS26_06805, bile acid hydrolase, bile salt hydrolase, Bile-Salt-Hydrolase, BSH, BSH A, BSH B, BSH C, BSH1, BSH12, BSH2, BSH3, BSH4, BSH47, BSH56, BSHA, BSHB, BSHC, BT2086, C3745_01535, CBAH, CBH, CBSHalpha, CBSHbeta, CGH, cholylglycine hydrolase, Conjugated bile acid hydrolase, conjugated bile salt hydrolase, conjugated bile salt hydrolase alpha peptide, conjugated bile salt hydrolase beta, EFBG_01849, EfBSH, glycocholase, LaciP, LgBSH, linear amide C-N hydrolase, LJ1412, LJ_0056, LJ_1147, LsalN1, lsBSH, More, probiotic bile salt hydrolase, salt hydrolase

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.24 choloylglycine hydrolase

KI Value

KI Value on EC 3.5.1.24 - choloylglycine hydrolase

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.86
4-amino-phenylacetic acid
-
pH 6.5, 40°C, recombinant wild-type enzyme
2
benzyl penicillin
-
pH 6.5, 40°C, recombinant wild-type enzyme
4.7
cholate
-
pH 8.0, 50°C
0.32
cholic acid
-
pH 6.5, 40°C, recombinant wild-type enzyme
0.46
deoxycholic acid
-
pH 6.5, 40°C, recombinant wild-type enzyme
1.2
phenoxy penicillin
-
pH 6.5, 40°C, recombinant wild-type enzyme
0.82
phenoxyacetic acid
-
pH 6.5, 40°C, recombinant wild-type enzyme
0.94
phenylacetic acid
-
pH 6.5, 40°C, recombinant wild-type enzyme
2.5
taurine
-
pH 8.0, 50°C
2.5
taurocholic acid
-
pH 8.0, 50°C
additional information
additional information
-
inhibition kinetics
-