3.4.24.70: oligopeptidase A
This is an abbreviated version!
For detailed information about oligopeptidase A, go to the full flat file.
Word Map on EC 3.4.24.70
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3.4.24.70
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prolyl
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typhimurium
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dipeptidyl
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carboxypeptidase
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neuropeptides
-
endopeptidases
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oxyanion
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subtilisin
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octapeptide
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post-proline
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thimet
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neurolysin
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z-pro-prolinal
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bell-shaped
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product-like
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scissile
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3.4.24.15
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arrhenius
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metallopeptidase
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bradykinin
- 3.4.24.70
-
prolyl
- typhimurium
-
dipeptidyl
- carboxypeptidase
- neuropeptides
- endopeptidases
-
oxyanion
- subtilisin
- octapeptide
-
post-proline
-
thimet
- neurolysin
- z-pro-prolinal
-
bell-shaped
-
product-like
-
scissile
-
3.4.24.15
-
arrhenius
- metallopeptidase
- bradykinin
Reaction
hydrolysis of oligopeptides, with broad specificity. Gly or Ala commonly occur as P1 or P1' residues, but additional information distant residues are also important, as is shown by the fact that Z-Gly-Pro-Gly-/-Gly-Pro-Ala is cleaved, but not Z-(Gly)5 =
Synonyms
68000-M Signalpeptide hydrolase, More, oligopeptidase A, OpdA, prlC, TOP, Top1, Top2
ECTree
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Metals Ions
Metals Ions on EC 3.4.24.70 - oligopeptidase A
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Co2+
Cu2+
Mn2+
Zn2+
additional information
Mn2+
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activation, to a lesser extent than Co2+, 0.1 mM
additional information
OpdA is a metalloproteinase
additional information
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putative Zn2+-binding site