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3.4.24.70: oligopeptidase A

This is an abbreviated version!
For detailed information about oligopeptidase A, go to the full flat file.

Word Map on EC 3.4.24.70

Reaction

hydrolysis of oligopeptides, with broad specificity. Gly or Ala commonly occur as P1 or P1' residues, but additional information distant residues are also important, as is shown by the fact that Z-Gly-Pro-Gly-/-Gly-Pro-Ala is cleaved, but not Z-(Gly)5 =

Synonyms

68000-M Signalpeptide hydrolase, More, oligopeptidase A, OpdA, prlC, TOP, Top1, Top2

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.70 oligopeptidase A

KCat KM Value

KCat KM Value on EC 3.4.24.70 - oligopeptidase A

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
595
Abz-GASPFRQ-EDDnp
-
pH 7.4, 37°C, recombinant wild-type enzyme
49
Abz-GDSPFRQ-EDDnp
-
pH 7.4, 37°C, recombinant wild-type enzyme
42
Abz-GESPFRQ-EDDnp
-
pH 7.4, 37°C, recombinant wild-type enzyme
1584
Abz-GFSPFRQ-EDDnp
-
pH 7.4, 37°C, recombinant wild-type enzyme
194
Abz-GGSPFRQ-EDDnp
-
pH 7.4, 37°C, recombinant wild-type enzyme
1920
Abz-GHSPFRQ-EDDnp
-
pH 7.4, 37°C, recombinant wild-type enzyme
1095
Abz-GKSPFRQ-EDDnp
-
pH 7.4, 37°C, recombinant wild-type enzyme
844
Abz-GLSPFRQ-EDDnp
-
pH 7.4, 37°C, recombinant wild-type enzyme
273
Abz-GNSPFRQ-EDDnp
-
pH 7.4, 37°C, recombinant wild-type enzyme
159
Abz-GPSPFRQ-EDDnp
-
pH 7.4, 37°C, recombinant wild-type enzyme
258
Abz-GQSPFRQ-EDDnp
-
pH 7.4, 37°C, recombinant wild-type enzyme
10360
Abz-GRSPFRQ-EDDnp
-
pH 7.4, 37°C, recombinant wild-type enzyme
590
Abz-GSSPFRQ-EDDnp
-
pH 7.4, 37°C, recombinant wild-type enzyme
2191
Abz-GYSPFRQ-EDDnp
-
pH 7.4, 37°C, recombinant wild-type enzyme