3.4.24.64: mitochondrial processing peptidase

This is an abbreviated version!
For detailed information about mitochondrial processing peptidase, go to the full flat file.

Word Map on EC 3.4.24.64

Reaction

Release of N-terminal targetting peptides from precursor proteins imported into the mitochondrion, typically with Arg in position P2 =

Synonyms

More, Processing enhancing peptidase, Proteinase, mitochondrial protein precursor-processing, Matrix peptidase, Matrix processing peptidase, Matrix processing proteinase, Mitochondrial protein precursor-processing proteinase, MPP, Mitochondrial chelator-sensitive protease, General mitochondrial processing peptidase, TPP, processing peptidase, Alpha-MPP, Beta-MPP, HA1523, P-52, P-55, PEP, processing enhancing protein, Mas1, Mas2, Plsp1, Atp23, inner membrane peptidase processing enzyme, Imp1, Imp2, mitochondrial processing peptidase, HPP, GPP, TTHA1264, thylakoidal processing peptidase, Plsp2, MPP-alpha, MMP-beta, mitochondrial processing peptidase-alpha protein, PMPCA, mitochondrial processing protease

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.64 mitochondrial processing peptidase

KM Value

KM Value on EC 3.4.24.64 - mitochondrial processing peptidase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0034
Abz-FQTKVAAK(Dnp)-NH2
pH 8.0, 25°C
0.000941
Abz-FRSGQPLQNKVQLQ-ED(Dnp)
pH 8.0, 25°C
0.0013
Abz-FSSKTTVK(Dnp)-NH2
pH 8.0, 25°C
0.0011
Abz-IKQSSLLK(Dnp)-NH2
pH 8.0, 25°C
0.0042
Abz-MTAALKTK(Dnp)-NH2
pH 8.0, 25°C
0.0013
Abz-NLMKKSTK(Dnp)-NH2
pH 8.0, 25°C
0.0051
Abz-QPLANKVQ-ED(Dnp)
pH 8.0, 25°C
0.0032
Abz-QPLQAKVQ-ED(Dnp)
pH 8.0, 25°C
0.0029
Abz-QPLQNKVQ-ED(Dnp)
pH 8.0, 25°C
0.00085
Abz-TTKLKAAK(Dnp)-NH2
pH 8.0, 25°C
0.01
Abz-VAAQTKTK(Dnp)-NH2
pH 8.0, 25°C
0.0019
Abz-VISSRLEK(Dnp)-NH2
pH 8.0, 25°C
0.0018
Abz-VRNFRSGQPLQNKVQ-ED(Dnp)
pH 8.0, 25°C
0.0062
Abz-WTTGGKAK(Dnp)-NH2
pH 8.0, 25°C
0.0425
ARAARAARAFAASA
-
pH 7.4, 30°C
0.0215
ARAARAARAFASAA
-
pH 7.4, 30°C
0.0074
ARAARAARAFATSA
-
pH 7.4, 30°C
0.0296
ARAARAARAFSAAA
-
pH 7.4, 30°C
0.0294
ARAARAARAFSASA
-
pH 7.4, 30°C
0.0173
ARAARAARAFSCSA
-
pH 7.4, 30°C
0.0095
ARAARAARAFSSAA
-
pH 7.4, 30°C
0.0086
ARAARAARAFSSSA
-
pH 7.4, 30°C
0.0038
ARAARAARAFSTAA
-
pH 7.4, 30°C
0.0031
ARAARAARAFSTSA
-
pH 7.4, 30°C
0.0165
ARAARAARAFSVSA
-
pH 7.4, 30°C
0.0103 - 0.015
ARAARAARAFTSSA
0.0098 - 0.0101
ARAARAARAYGSTA
0.0108
ARAARAARAYSSTA
-
pH 7.4, 30°C
0.0079
ARAARAARAYSTTA
-
pH 7.4, 30°C
0.000063 - 0.00091
MDH1-21
-
additional information
additional information
-
half-maximal processing of in vitro synthesized precursors to their respective mature forms: F1-ATPase beta-subunit at 1.5 min, cytochrome b2 at 22 min and cytochrome c oxidase at 4 min
-