3.4.24.60: dactylysin

This is an abbreviated version!
For detailed information about dactylysin, go to the full flat file.

Word Map on EC 3.4.24.60

3.4.24.60

metalloendopeptidase

dibasic

convertase

n-arginine

ectodomain

factor-like

adam17

heparin-binding

disintegrin

hb-egf

Reaction

Hydrolysis of peptides of at least six residues, with bulky hydrophobic residues in the P1' position. Shows a preference for hydrophobic doublets such as -Phe-/-Phe- and -Phe-/-Leu- in somatostatin-(1-14)-peptide and dynorphin A-(1-6)-peptide, respectively =

Synonyms

Peptide hormone inactivating endopeptidase, peptide hormone inactivating enzyme, PHIE

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.24 Metalloendopeptidases

3.4.24.60 dactylysin

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Results	in table
1	CAS Registry Number
1	General Stability
46	Inhibitors
3	Ki Value [mM]
40	KM Value [mM]
1	Localization
3	Metals/Ions
3	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
4	Organism
2	pH Optimum
1	pH Range
1	pH Stability
4	Purification (Commentary)
1	Reaction
1	Reaction Type
4	Reference
4	Source Tissue
1	Specific Activity [micromol/min/mg]
1	Storage Stability
79	Substrates and Products (Substrate)
1	Subunits
4	Synonyms
1	Temperature Optimum [°C]

KM Value

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KM Value on EC 3.4.24.60 - dactylysin

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0.091

(19-28)ANF peptide