3.4.24.53: trimerelysin II
This is an abbreviated version!
For detailed information about trimerelysin II, go to the full flat file.
Word Map on EC 3.4.24.53
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3.4.24.53
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venom
-
snake
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flavoviridis
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hemorrhagic
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crotalus
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metalloproteinases
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atrox
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zinc-chelating
-
toxin
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atrolysin
-
rattlesnake
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non-hemorrhagic
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thermolysin
-
lysyl
-
medicine
- 3.4.24.53
- venom
-
snake
- flavoviridis
-
hemorrhagic
- crotalus
- metalloproteinases
- atrox
-
zinc-chelating
- toxin
- atrolysin
- rattlesnake
-
non-hemorrhagic
- thermolysin
-
lysyl
- medicine
Reaction
Cleavage of Asn3-/-Gln, His10-/-Leu and Ala14-/-Leu in the insulin B chain, and the bond Z-Gly-Pro-/-Leu-Gly-Pro in a small molecule substrate of microbial collagenase =
Synonyms
H2 metalloproteinase, H2-Proteinase, Proteinase H2, Trimeresurus metalloendopeptidase II
ECTree
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Substrates Products
Substrates Products on EC 3.4.24.53 - trimerelysin II
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REACTION DIAGRAM
Benzyloxycarbonyl-Gly-Pro-Leu-Gly-Pro + H2O
Benzyloxycarbonyl-Gly-Pro + Leu-Gly-Pro
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-
-
?
o-aminobenzoyl-peptide-2,4-dinitroanilinoethylamide + H2O
?
-
-
-
-
?
Oxidized insulin B-chain + H2O
Hydrolyzed oxidized insulin B-chain
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cleavage at Asn3-Gln4, His10-Leu11 and Ala14-Leu15
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?
additional information
?
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-
completely free from hemorrhagic acitivity
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-
?