Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

3.4.24.53: trimerelysin II

This is an abbreviated version!
For detailed information about trimerelysin II, go to the full flat file.

Word Map on EC 3.4.24.53

Reaction

Cleavage of Asn3-/-Gln, His10-/-Leu and Ala14-/-Leu in the insulin B chain, and the bond Z-Gly-Pro-/-Leu-Gly-Pro in a small molecule substrate of microbial collagenase =

Synonyms

H2 metalloproteinase, H2-Proteinase, Proteinase H2, Trimeresurus metalloendopeptidase II

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.53 trimerelysin II

Substrates Products

Substrates Products on EC 3.4.24.53 - trimerelysin II

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
Benzyloxycarbonyl-Gly-Pro-Leu-Gly-Pro + H2O
Benzyloxycarbonyl-Gly-Pro + Leu-Gly-Pro
show the reaction diagram
-
-
-
?
casein + H2O
hydrolyzed casein
show the reaction diagram
-
-
-
?
Fibrinogen + H2O
?
show the reaction diagram
-
-
-
-
?
o-aminobenzoyl-peptide-2,4-dinitroanilinoethylamide + H2O
?
show the reaction diagram
-
-
-
-
?
Oxidized insulin B-chain + H2O
Hydrolyzed oxidized insulin B-chain
show the reaction diagram
-
cleavage at Asn3-Gln4, His10-Leu11 and Ala14-Leu15
-
?
additional information
?
-
-
completely free from hemorrhagic acitivity
-
-
?