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3.4.24.51: ophiolysin

This is an abbreviated version!
For detailed information about ophiolysin, go to the full flat file.

Reaction

Cleavage of Asn3-/-Gln, Gln4-/-His, His10-/-Leu, Ala14-/-Leu, and Tyr16-/-Leu in insulin B chain =

Synonyms

ohagin, Ophiophagus metalloendopeptidase

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.51 ophiolysin

Reference

Reference on EC 3.4.24.51 - ophiolysin

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Yamakawa, Y.; Omori-Satoh, T.
A protease in the venom of king cobra (Ophiophagus hannah): purification, characterization and substrate specificity on oxidized insulin B-chain
Toxicon
26
1145-1155
1988
Ophiophagus hannah
Manually annotated by BRENDA team
Yamakawa, Y.
Ophiolysin
Handbook Of Proteolytic Enzymes(Barrett,A. J. ,Rawlings,N. D. ,Woessner,J. F. ,Eds. )Academic Press
1
699-701
2004
Ophiophagus hannah
-
Manually annotated by BRENDA team
Guo, X.; Zeng, L.; Lee, W.; Zhang, Y.; Jin, Y.
Isolation and cloning of a metalloproteinase from king cobra snake venom
Toxicon
49
954-965
2007
Ophiophagus hannah (A3R0T9), Ophiophagus hannah
Manually annotated by BRENDA team