3.4.24.50: bothrolysin

This is an abbreviated version!
For detailed information about bothrolysin, go to the full flat file.

Word Map on EC 3.4.24.50

Reaction

Cleavage of Gln4-/-His, Ser9-/-His and Ala14-/-Leu of insulin B chain and Pro-/-Phe of angiotensin I =

Synonyms

Bothrops metalloendopeptidase J, J Protease

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.50 bothrolysin

Inhibitors

Inhibitors on EC 3.4.24.50 - bothrolysin

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1,10-phenanthroline
5,5'-dithiobis(2-nitrobenzoic acid)
-
1 mM: 70% inhibition, in presence of 2 mM Ca2+: 30% inhibition
DM43
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serum from opossum, inhibits the fibrinogenolytic activity of bothrolysin and forms a stable complex with it
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DTNB
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inhibitory, partially prevented by addition of Ca2+
Protein inhibitor
-
from blood plasma of Bothrops jararaca, completely inhibits
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additional information
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