This is an abbreviated version!
For detailed information about bothrolysin, go to the full flat file.
Cleavage of Gln4-/-His, Ser9-/-His and Ala14-/-Leu of insulin B chain and Pro-/-Phe of angiotensin I =
Bothrops metalloendopeptidase J, J Protease
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Inhibitors on EC 184.108.40.206 - bothrolysin
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1 mM: 70% inhibition, in presence of 2 mM Ca2+: 30% inhibition
serum from opossum, inhibits the fibrinogenolytic activity of bothrolysin and forms a stable complex with it
from blood plasma of Bothrops jararaca, completely inhibits
phosphoramidon, leupeptin, epoxysuccinyl derivatives e.g. E-64, Ep-475 or Ep-479, all 0.5 mM, are no inhibitors