3.4.24.47: horrilysin

This is an abbreviated version!
For detailed information about horrilysin, go to the full flat file.

Reaction

Cleavage of only the single bond Ala14-/-Leu in the insulin B chain, Ser12-/-Leu in the A chain, and Ile-/-Gly, Pro-/-Ala, and Ser-/-Trp in melittin =

Synonyms

Crotalus horridus metalloendopeptidase, Hemorrhagic proteinase IV, HP-IV, Proteinase, Crotalus horridus horridus venom hemorrhagic

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.24 Metalloendopeptidases

                3.4.24.47 horrilysin

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
1	Application
1	CAS Registry Number
2	General Stability
4	Inhibitors
7	Metals/Ions
4	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
3	Organism
2	pH Optimum
1	Posttranslational Modification
2	Purification (Commentary)
1	Reaction
1	Reaction Type
3	Reference
3	Source Tissue
1	Storage Stability
31	Substrates and Products (Substrate)
2	Subunits
5	Synonyms
2	Temperature Optimum [°C]

General Stability

print visible entries

print all entries

General Stability on EC 3.4.24.47 - horrilysin

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide Go to General Stability Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

GENERAL STABILITY

ORGANISM

UNIPROT

LITERATURE

Extensive dialysis against distilled water inactivates, incubation with Zn2+, Ca2+ or Mg2+ fails to reconstitute activity

Crotalus horridus horridus

-

31286

Stable to dialysis against 0.2 M Tris buffer, pH 7.5

Crotalus horridus horridus

-

31286