3.4.24.46: adamalysin
This is an abbreviated version!
For detailed information about adamalysin, go to the full flat file.
Word Map on EC 3.4.24.46
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3.4.24.46
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metalloproteinases
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disintegrin
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snake
-
metzincins
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electrotransfer
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adam15
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astacins
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matrixins
-
alpha-secretase
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met-turn
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hexxhxxgxxh
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medicine
- 3.4.24.46
- metalloproteinases
-
disintegrin
-
snake
-
metzincins
-
electrotransfer
- adam15
- astacins
- matrixins
- alpha-secretase
-
met-turn
-
hexxhxxgxxh
- medicine
Reaction
Cleavage of Phe1-/-Val, His5-/-Leu, His10-/-Leu, Ala14-/-Leu, Leu15-/-Tyr, and Tyr16-/-Leu of insulin B chain =
Synonyms
Adamalysin II, Crotalus adamanteus metalloendopeptidase, Crotalus adamanteus venom proteinase II, metargidin, Proteinase I and II, Proteinase, Crotalus adamanteus venom, II
ECTree
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Metals Ions
Metals Ions on EC 3.4.24.46 - adamalysin
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Ca2+
Zn2+
Zn2+
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zinc-binding motif, almost tetrahedrally co-ordinated by His142, His146 and His152 and a water molecule anchored to an intermediate Glu residue, Glu143