3.4.24.44: atrolysin E
This is an abbreviated version!
For detailed information about atrolysin E, go to the full flat file.
Word Map on EC 3.4.24.44
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3.4.24.44
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venom
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rattlesnake
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diamondback
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snake
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metalloproteinase
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disintegrins
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zymogen
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spacer
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raman
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proteinases
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medicine
- 3.4.24.44
- venom
- rattlesnake
-
diamondback
-
snake
- metalloproteinase
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disintegrins
- zymogen
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spacer
-
raman
- proteinases
- medicine
Reaction
Cleavage of Asn3-/-Gln, Ser9-/-His and Ala14-/-Leu bonds in insulin B chain and Tyr14-/-Gln and Thr8-/-Ser in A chain. Cleaves type IV collagen at Ala73-/-Gln in alpha1(IV) and at Gly7-/-Leu in alpha2(IV) =
Synonyms
atrolysin E/D, Crotalus atrox metalloendopeptidase e, Hemorrhagic toxin e, HT-e
ECTree
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Reference
Reference on EC 3.4.24.44 - atrolysin E
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Fox, J.W.; Bjarnason, J.B.
Atrolysins: metalloproteinases from Crotalus atrox venom
Methods Enzymol.
248
368-387
1995
Crotalus atrox
Bjarnason, J.B.; Hamilton, D.; Fox, J.W.
Studies on the mechanism of hemorrhage production by five proteolytic hemorrhagic toxins from Crotalus atrox venom
Biol. Chem. Hoppe-Seyler
369
121-129
1988
Crotalus atrox
Bjarnason, J.B.; Tu, A.T.
Hemorrhagic toxins from Western diamondback rattlesnake (Crotalus atrox) venom: isolation and characterization of five toxins and the role of zinc in hemorrhagic toxin e
Biochemistry
17
3395-3404
1978
Crotalus atrox
Bjarnason, J.B.; Fox, J.W.
Proteolytic specificity and cobalt exchange of hemorrhagic toxin e, a zinc protease isolated from the venom of the western diamondback rattlesnake (Crotalus atrox)
Biochemistry
22
3770-3778
1983
Crotalus atrox
Shimokawa, K.i.; Jia, L.G.; Shannon, J.D.; Fox, J.W.
Isolation, sequence analysis, and biological activity of atrolysin E/D, the non-RGD disintegrin domain from Crotalus atrox venom
Arch. Biochem. Biophys.
354
239-246
1998
Crotalus atrox
Fox, J.W.; Bjarnason, J.B.
Atrolysin E
Handbook Of Proteolytic Enzymes(Barrett,A. J. ,Rawlings,N. D. ,Woessner,J. F. ,Eds. )Academic Press
1
674-676
2004
Crotalus atrox
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