3.4.24.44: atrolysin E
This is an abbreviated version!
For detailed information about atrolysin E, go to the full flat file.
Word Map on EC 3.4.24.44
-
3.4.24.44
-
venom
-
rattlesnake
-
diamondback
-
snake
-
metalloproteinase
-
disintegrins
-
zymogen
-
spacer
-
raman
-
proteinases
-
medicine
- 3.4.24.44
- venom
- rattlesnake
-
diamondback
-
snake
- metalloproteinase
-
disintegrins
- zymogen
-
spacer
-
raman
- proteinases
- medicine
Reaction
Cleavage of Asn3-/-Gln, Ser9-/-His and Ala14-/-Leu bonds in insulin B chain and Tyr14-/-Gln and Thr8-/-Ser in A chain. Cleaves type IV collagen at Ala73-/-Gln in alpha1(IV) and at Gly7-/-Leu in alpha2(IV) =
Synonyms
atrolysin E/D, Crotalus atrox metalloendopeptidase e, Hemorrhagic toxin e, HT-e
ECTree
Advanced search results
Application
Application on EC 3.4.24.44 - atrolysin E
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
medicine
-
one of the most hemorrhagic metalloproteinases of the P-II class in the venom, causes extensive hemorrhage in muscle tissue and extensive degeneration of capillaries, degradation of basement membrane proteins and surrounding stroma, its free disintegrin domain possesses platelet-aggregation inhibitory activity