Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

3.4.24.27: thermolysin

This is an abbreviated version!
For detailed information about thermolysin, go to the full flat file.

Word Map on EC 3.4.24.27

Reaction

preferential cleavage: -/-Leu > -/-Phe =

Synonyms

Bacillus thermoproteolyticus neutral proteinase, EC 3.4.24.4, hspA, LIC13322, Neutral metalloproteinase, NprM, protease type X, proteinase type X, Proteinase, Bacillus thermoproteolyticus neutral, protex 14L, Thermoase, thermoase PC10F, Thermoase Y10, thermolysin, thermolysin-like protease, Thermostable neutral proteinase, TL, TLN, TLP, TLP-ste

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.27 thermolysin

Organic Solvent Stability

Organic Solvent Stability on EC 3.4.24.27 - thermolysin

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
ORGANIC SOLVENT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
2-methyl-2-butanol
dimethylformamide
-
half-life is 6 min at 80°C, trehalose stabilizes the enzyme in DMF
DMSO
-
half-life is over 20 min at 80°C
isopropanol
-
half-life is 4 min at 80°C, stabilizes the enzyme
n-propanol
-
half-life is 3 min at 80°C, glycerol stabilizes the enzyme
additional information
-
solvents cause mixed inhibition of thermolysin, kinetic and structural studies, overview