3.4.24.26: pseudolysin

This is an abbreviated version!
For detailed information about pseudolysin, go to the full flat file.

Word Map on EC 3.4.24.26

Reaction

Hydrolysis of proteins including elastin, collagen types III and IV, fibronectin and immunoglobulin A, generally with bulky hydrophobic group at P1'. Insulin B chain cleavage pattern identical to that of thermolysin, but specificity differs in other respects =

Synonyms

More, EC 3.4.24.4, Pseudomonas elastase, Pseudomonas aeruginosa neutral metalloproteinase, elastase, PE, PASP, Neutral metalloproteinase, Pseudomonas aeruginosa elastase, LasB, PAE, Pseudomonas aeruginosa small protease, PsE, elastase B, Pseudomonas protease, EPa, elastolytic metalloproteinase, aeruginolysin, LepA, A2 elastase, ealastase LasB, LasB protease

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.26 pseudolysin

pH Range

pH Range on EC 3.4.24.26 - pseudolysin

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
4 - 7
-
no activity at pH 2.0, the enzyme can resist and be active at low pH values e.g. in the human stomach
5 - 10
-
activity range, profile overview