3.4.24.26: pseudolysin

This is an abbreviated version!
For detailed information about pseudolysin, go to the full flat file.

Word Map on EC 3.4.24.26

3.4.24.26

thermolysin

metalloproteinases

collagenase

metalloprotease

3.4.24.4

elastin

gelatinase

elastases

phosphoramidon

pseudomonal

stromelysin

thermolysin-like

metalloendopeptidase

medicine

thermoproteolyticus

aureolysin

vibriolysin

intrastromal

industry

nutrition

biotechnology

synthesis

pharmacology

diagnostics

Reaction

Hydrolysis of proteins including elastin, collagen types III and IV, fibronectin and immunoglobulin A, generally with bulky hydrophobic group at P1'. Insulin B chain cleavage pattern identical to that of thermolysin, but specificity differs in other respects =

Synonyms

A2 elastase, aeruginolysin, ealastase LasB, EC 3.4.24.4, elastase, elastase B, elastolytic metalloproteinase, EPa, LasB, LasB protease, LepA, More, Neutral metalloproteinase, PAE, PASP, PE, PsE, Pseudomonas aeruginosa elastase, Pseudomonas aeruginosa neutral metalloproteinase, Pseudomonas aeruginosa small protease, Pseudomonas elastase, Pseudomonas protease

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.24 Metalloendopeptidases

3.4.24.26 pseudolysin

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
6	Activating Compound
26	AA Sequence
24	Application
1	CAS Registry Number
14	Cloned(Commentary)
4	Crystallization (Commentary)
2	Expression
25	General Information
2	General Stability
24	IC50 Value
155	Inhibitors
18	Ki Value [mM]
26	KM Value [mM]
39	Localization
25	Metals/Ions
39	Molecular Weight [Da]
18	Natural Substrates/ Products (Substrates)
31	Organic Solvent Stability
87	Organism
3	PDB ID
18	pH Optimum
2	pH Range
7	pH Stability
3	pI Value
6	Posttranslational Modification
26	Protein Variants
30	Purification (Commentary)
1	Reaction
1	Reaction Type
83	Reference
2	Renatured (Commentary)
4	Source Tissue
9	Specific Activity [micromol/min/mg]
1	Storage Stability
215	Substrates and Products (Substrate)
28	Subunits
95	Synonyms
14	Temperature Optimum [°C]
3	Temperature Range [°C]
15	Temperature Stability [°C]
28	Turnover Number [1/s]

Metals Ions

print visible entries

print all entries

Metals Ions on EC 3.4.24.26 - pseudolysin

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide

Go to Metals and Ions Search

Ca2+

Pseudomonas aeruginosa

a calcium ion is also required for enzyme activity, and stabilizes its tertiary structure. Contact with the calcium ion is made by the carboxyl groups of Asp136, Glu172, Glu175, and Asp183, the carbonyl group of Leu185, and one water molecule

733746

Mn2+

Pseudomonas aeruginosa

inhibits activity at 10 mM

664291

Ni2+

Pseudomonas aeruginosa

inhibits activity at 10 mM

664291

Zinc

8 entries

Zn2+

9 entries

additional information

4 entries