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3.4.24.25: vibriolysin

This is an abbreviated version!
For detailed information about vibriolysin, go to the full flat file.

Word Map on EC 3.4.24.25

Reaction

Preferential cleavage of bonds with bulky hydrophobic groups in P2 and P1'. Phe at P1' is the most favoured residue, which distinguished this enzyme from thermolysin =

Synonyms

Aeromonas neutral protease, Aeromonas proteolytica neutral proteinase, Aeromonolysin, E495, EC 3.4.24.4, HA/protease, hAPA, hemagglutinin/protease HA/P, MCP-02, MvP1, NprV-R, Proteinase, Aeromonas proteolytica neutral, Vibriolysin

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.25 vibriolysin

Reference

Reference on EC 3.4.24.25 - vibriolysin

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Wilkes, S.H.; Prescott, J.M.
Aeromonas neutral protease
Methods Enzymol.
45
404-415
1976
Vibrio proteolyticus
Manually annotated by BRENDA team
Wilkes, S.H.; Bayliss, M.E.; Prescott, J.M.
Critical ionizing groups in Aeromonas neutral protease
J. Biol. Chem.
263
1821-1825
1988
Vibrio proteolyticus
Manually annotated by BRENDA team
Bayliss, M.E.; Wilkes, S.H.; Prescott, J.M.
Aeromonas neutral protease: specificity toward extended substrates
Arch. Biochem. Biophys.
204
214-219
1980
Vibrio proteolyticus
Manually annotated by BRENDA team
Holmquist, B.; Vallee, B.L.
Esterase activity of zinc neutral proteases
Biochemistry
15
101-107
1976
Vibrio proteolyticus
Manually annotated by BRENDA team
Adekoya, O.A.; Helland, R.; Willassen, N.P.; Sylte, I.
Comparative sequence and structure analysis reveal features of cold adaptation of an enzyme in the thermolysin family
Proteins
62
435-449
2006
Antarctic bacterium str. 643 (Q9KH34)
Manually annotated by BRENDA team
Lutfullah, G.; Amin, F.; Khan, Z.; Azhar, N.; Azim, M.K.; Noor, S.; Shoukat, K.
Homology modeling of hemagglutinin/protease [HA/P (vibriolysin)] from Vibrio cholerae: Sequence comparision, residue interactions and molecular mechanism
Protein J.
27
105-114
2008
Vibrio cholerae (P24153)
Manually annotated by BRENDA team
Bjornsdottir, B.; Fast, M.D.; Sperker, S.A.; Brown, L.L.; Gudmundsdottir, B.K.
Effects of Moritella viscosa antigens on pro-inflammatory gene expression in an Atlantic salmon (Salmo salar Linnaeus) cell line (SHK-1)
Fish Shellfish Immunol.
26
858-863
2009
Moritella viscosa (B5AX16), Moritella viscosa
Manually annotated by BRENDA team
Sonoda, H.; Sugimura, A.
Extracellular production of active vibriolysin engineered by random mutagenesis in Escherichia coli
Protein Expr. Purif.
62
153-159
2008
Vibrio proteolyticus (Q00971), Vibrio proteolyticus
Manually annotated by BRENDA team
Bjornsdottir, B.; Fridjonsson, O.H.; Magnusdottir, S.; Andresdottir, V.; Hreggvidsson, G.O.; Gudmundsdottir, B.K.
Characterisation of an extracellular vibriolysin of the fish pathogen Moritella viscosa
Vet. Microbiol.
136
326-334
2008
Moritella viscosa (B5AX16), Moritella viscosa
Manually annotated by BRENDA team
Sonoda, H.; Daimon, K.; Yamaji, H.; Sugimura, A.
Efficient production of active Vibrio proteolyticus aminopeptidase in Escherichia coli by co-expression with engineered vibriolysin
Appl. Microbiol. Biotechnol.
84
191-198
2009
Vibrio proteolyticus
Manually annotated by BRENDA team
Xie, B.B.; Bian, F.; Chen, X.L.; He, H.L.; Guo, J.; Gao, X.; Zeng, Y.X.; Chen, B.; Zhou, B.C.; Zhang, Y.Z.
Cold adaptation of zinc metalloproteases in the thermolysin family from deep sea and arctic sea ice bacteria revealed by catalytic and structural properties and molecular dynamics: new insights into relationship between conformational flexibility and hydr
J. Biol. Chem.
284
9257-9269
2009
Pseudoalteromonas sp. SM9913 (A1DRD5), Pseudoalteromonas sp. SM495 (B6E623)
Manually annotated by BRENDA team
Iqbal, A.; Azim, M.K.; Hashmi, N.; Ali, S.A.; Musharaf, S.G.
Structural characterization of metalloprotease vibriolysin of cholera pathogen Vibrio cholerae
Protein Pept. Lett.
18
287-294
2011
Vibrio cholerae serotype O1
Manually annotated by BRENDA team
Benitez, J.A.; Silva, A.J.
Vibrio cholerae hemagglutinin(HA)/protease An extracellular metalloprotease with multiple pathogenic activities
Toxicon
115
55-62
2016
Vibrio cholerae
Manually annotated by BRENDA team