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3.4.24.20: peptidyl-Lys metalloendopeptidase

This is an abbreviated version!
For detailed information about peptidyl-Lys metalloendopeptidase, go to the full flat file.

Word Map on EC 3.4.24.20

Reaction

Preferential cleavage in proteins: -Xaa-/-Lys- (in which Xaa may be Pro) =

Synonyms

Am-LysN, Armillaria mellea neutral proteinase, aspzincin metalloendopeptidase, aspzincin metalloprotease, EC 3.4.99.30, EC 3.4.99.32, GFMEP, Lys-N, LysN, MEP, peptidyl-Lys metalloendopeptidase, peptidyl-Lys metallopeptidase, Peptidyllysine metalloproteinase, POMEP, Proteinase, peptidyllysine metallo-

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.20 peptidyl-Lys metalloendopeptidase

Inhibitors

Inhibitors on EC 3.4.24.20 - peptidyl-Lys metalloendopeptidase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1,10-phenanthroline
2,2'-bipyridine
2,4-dinitrophenyl-Ala-Thr-D-lysine-Leu-Ser-Try
-
2-mercaptoethanol
6-aminohexanoic acid
-
caseinolytic activity
Ag2+
-
1 mM, strong
agmatine
-
caseinolytic activity
antipain
Ba2+
-
1 mM, weak, caseinolytic activity
Ca2+
-
1 mM, weak, caseinolytic activity
Co2+
-
0.1 mM, caseinolytic activity
dithiothreitol
DL-homoarginine
-
caseinolytic activity
ethylamine
-
-
Guanidine-HCl
-
2 M and above, not at 1 M
imidazole
-
-
L-aminobutyric acid
-
caseinolytic activity
L-arginine
L-lysine
L-Lysine ethylester
-
caseinolytic activity
L-ornithine
methylamine
-
-
N-ethylmaleimide
n-Propylamine
-
-
p-chloromercuribenzoate
phosphoramidon
S-2-aminoethylcysteine
-
-
SDS
-
0.1% and above, not at 0.01%
Sodium citrate
-
0.1 M, not 0.01 M
tosyl-Lys chloromethyl ketone
tosyl-Phe chloromethyl ketone
-
weak, caseinolytic activity
Urea
-
5 M, not at 2 M
additional information
-