3.4.23.4: chymosin

This is an abbreviated version!
For detailed information about chymosin, go to the full flat file.

Word Map on EC 3.4.23.4

3.4.23.4

milk

casein

cheese

pepsin

calf

coagulation

kappa-caseins

rennet

milk-clotting

clot

proteinases

angiotensin

hypertension

aldosterone

beta-caseins

micelle

whey

pepsinogen

renin

ripening

plasmin

zymogen

curd

camel

skim

mucor

cheddar

pepstatin

abomasum

gelation

cardunculus

preruminant

cynara

progastricsins

miehei

fundic

beta-cn

food industry

pusillus

gastricsins

urea-page

s1-casein

beta-lactoglobulin

parasitica

hypokalemia

glycomacropeptide

cheese-making

rhizomucor

3.4.23.1

synthesis

Reaction

Broad specificity similar to that of pepsin A. Clots milk by cleavage of a single Ser-Phe105-/-Met-Ala bond in kappa-chain of casein =

Synonyms

CHY-MAX, CHY-MAX 200, chymase, chymosin, chymosin A, chymosin B, CYM, EC 3.4.4.3, More, Preprorennin, prochymosin, rCH, rennin

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.23 Aspartic endopeptidases

3.4.23.4 chymosin

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Results	in table
3	Activating Compound
30	AA Sequence
14	Application
1	CAS Registry Number
28	Cloned(Commentary)
10	Crystallization (Commentary)
212	Disease/ Diagnostics
1	General Information
1	General Stability
20	Inhibitors
4	kcat/KM [mM/s]
59	KM Value [mM]
1	Localization
9	Metals/Ions
20	Molecular Weight [Da]
61	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
83	Organism
9	PDB ID
20	pH Optimum
20	pH Range
10	pH Stability
2	pI Value
8	Posttranslational Modification
14	Protein Variants
22	Purification (Commentary)
1	Reaction
2	Reaction Type
83	Reference
3	Renatured (Commentary)
23	Source Tissue
3	Specific Activity [micromol/min/mg]
6	Storage Stability
180	Substrates and Products (Substrate)
25	Subunits
26	Synonyms
23	Temperature Optimum [°C]
11	Temperature Range [°C]
22	Temperature Stability [°C]
43	Turnover Number [1/s]

Posttranslational Modification

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Posttranslational Modification on EC 3.4.23.4 - chymosin

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glycoprotein

7 entries

additional information

Bos taurus

insertion of a glycosylation site (S351T), glycosylation has significant inhibitory effect but this can be circumvented by deglycosylation with endoglucosidase H

687865