3.4.23.4: chymosin

This is an abbreviated version!
For detailed information about chymosin, go to the full flat file.

Word Map on EC 3.4.23.4

3.4.23.4

milk

casein

cheese

pepsin

calf

coagulation

kappa-caseins

rennet

milk-clotting

clot

proteinases

angiotensin

hypertension

aldosterone

beta-caseins

micelle

whey

pepsinogen

renin

ripening

plasmin

zymogen

curd

camel

skim

mucor

cheddar

pepstatin

abomasum

gelation

cardunculus

preruminant

cynara

progastricsins

miehei

fundic

beta-cn

food industry

pusillus

gastricsins

urea-page

s1-casein

beta-lactoglobulin

parasitica

hypokalemia

glycomacropeptide

cheese-making

rhizomucor

3.4.23.1

synthesis

Reaction

Broad specificity similar to that of pepsin A. Clots milk by cleavage of a single Ser-Phe105-/-Met-Ala bond in kappa-chain of casein =

Synonyms

CHY-MAX, CHY-MAX 200, chymase, chymosin, chymosin A, chymosin B, CYM, EC 3.4.4.3, More, Preprorennin, prochymosin, rCH, rennin

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.23 Aspartic endopeptidases

3.4.23.4 chymosin

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
3	Activating Compound
30	AA Sequence
14	Application
1	CAS Registry Number
28	Cloned(Commentary)
10	Crystallization (Commentary)
212	Disease/ Diagnostics
1	General Information
1	General Stability
20	Inhibitors
4	kcat/KM [mM/s]
59	KM Value [mM]
1	Localization
9	Metals/Ions
20	Molecular Weight [Da]
61	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
83	Organism
9	PDB ID
20	pH Optimum
20	pH Range
10	pH Stability
2	pI Value
8	Posttranslational Modification
14	Protein Variants
22	Purification (Commentary)
1	Reaction
2	Reaction Type
83	Reference
3	Renatured (Commentary)
23	Source Tissue
3	Specific Activity [micromol/min/mg]
6	Storage Stability
180	Substrates and Products (Substrate)
25	Subunits
26	Synonyms
23	Temperature Optimum [°C]
11	Temperature Range [°C]
22	Temperature Stability [°C]
43	Turnover Number [1/s]

Engineering

print visible entries

print all entries

Engineering on EC 3.4.23.4 - chymosin

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide

Go to Protein Variants Search

A115T

Bos taurus

reduction of Km compared to wild-type

D304A

pH optima shift

D304A/T218A

G243D

increase of Km compared to wild-type

G244D

pH optima shift

Q288K

S351T

insertion of a glycosylation site in the linker region between chymosin and glucoamylase, strongly improves enzyme secretion

687865

T218A

Bos taurus

pH optima shift

36889, 36891, 36893

D289M/Q298L

Callithrix jacchus

decreased hydrolytic activity

667593

additional information

2 entries