3.4.23.32: Scytalidopepsin B
This is an abbreviated version!
For detailed information about Scytalidopepsin B, go to the full flat file.
Word Map on EC 3.4.23.32
-
3.4.23.32
-
subsite
-
dyad
-
scissile
-
beta-sandwich
-
rhythm
-
canaliculatum
-
ventricles
-
commenced
-
busycon
-
chymotrypsin
-
oxyanion
-
metoclopramide
-
atrial
-
aspergillopepsin
-
excitatory
-
neuromodulation
-
tetrahedral
-
whelk
-
beat
-
methysergide
- 3.4.23.32
-
subsite
-
dyad
-
scissile
-
beta-sandwich
-
rhythm
- canaliculatum
-
ventricles
-
commenced
- busycon
- chymotrypsin
-
oxyanion
- metoclopramide
-
atrial
- aspergillopepsin
-
excitatory
-
neuromodulation
-
tetrahedral
- whelk
-
beat
- methysergide
Reaction
Hydrolysis of proteins with broad specificity, cleaving Phe24-/-Phe, but not Leu15-Tyr and Phe25-Tyr in the B chain of insulin =
Synonyms
eqolisin, Ganoderma lucidum carboxyl proteinase, More, Proteinase, Ganoderma lucidum aspartic, Proteinase, Scytalidium lignicolum aspartic, B, SCP-B, Scytalidium aspartic proteinase B, Scytalidium lignicolum pepstatin-insensitive carboxyl peptidase, Scytalido-carboxyl peptidase-B, scytalidoglutamic peptidase, SGP, SLB
ECTree
3.4.23.32 Scytalidopepsin BAdvanced search results
results (
results (Inhibitors
Inhibitors on EC 3.4.23.32 - Scytalidopepsin B
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
INHIBITOR 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
acetyl-Phe--Lys-Phe-(3S,4S)-phenylstatinyl-Leu-Arg-NH2
-
SGP transition state mimic inhibitor
NaCl
-
a substantial decrease of the SGP catalytic efficiency (kcat/Km) is observed as the NaCl concentration is increases up to 1 M, while in the range up to 200 mM NaCl the effect is mainly in Km because there is no significant decrease in kcat values. A significant decrease in the kcat values is observed as the salt concentration is further increased from 200 to 800 mM NaCl
1,2-epoxy-3-(4-nitrophenoxy)propane
-
reacts with Glu53, which replaces one of the aspartic residues at the active centre
1,2-epoxy-3-(4-nitrophenoxy)propane
-
modifies active site residue Glu53
additional information
-
diazoacetyl-DL-norleucine methyl ester; methyl 2-diazoacetamidohexanoate; not: pepstatin Ac; Streptomyces-pepsin inhibitor (S-PI)
-
additional information
-
diazoacetyl-DL-norleucine methyl ester; diisopropyl fluorophosphate; EDTA; methyl 2-diazoacetamidohexanoate; microbial proteinase inhibitors (metal proteinase inhibitor, serine proteinase and thiol proteinase inhibitor); not: pepstatin Ac; PCMB; PMSF; Streptomyces-pepsin inhibitor (S-PI)
-
additional information
-
diazoacetyl-DL-norleucine methyl ester; diisopropyl fluorophosphate; EDTA; methyl 2-diazoacetamidohexanoate; Streptomyces-pepsin inhibitor (S-PI); sulfhydryl reagents
-
additional information
-
methyl 2-diazoacetamidohexanoate; not: pepstatin
-
additional information
-
diazoacetyl-DL-norleucine methyl ester; methyl 2-diazoacetamidohexanoate; Streptomyces-pepsin inhibitor (S-PI)
-
additional information
-
methyl 2-diazoacetamidohexanoate; not: pepstatin
-
additional information
-
the enzyme is insensitive to pepstatin and inhibitor S-PI, i.e. Ac-VV-statine-A-statine, statine is 4-amino-3-hydroxy-6-methylheptanoic acid, no inhibition by diazoacetyl-DL-norleucine methyl ester
-
