3.4.23.31: Scytalidopepsin A

This is an abbreviated version!
For detailed information about Scytalidopepsin A, go to the full flat file.

Reaction

Hydrolysis of proteins with specificity similar to that of pepsin A, but also cleaves Cys(SO3H)7-/-Gly and Leu17-/-Val in the B chain of insulin =

Synonyms

Proteinase, Scytalidium lignicolum aspartic, Proteinase, Scytalidium lignicolum aspartic, A-2, Proteinase, Scytalidium lignicolum aspartic, A-I, Proteinase, Scytalidium lignicolum aspartic, C-, Scytalidium aspartic proteinase A, Scytalidium lignicolum acid proteinase, Scytalidium lignicolum aspartic proteinase, Scytalidium lignicolum carboxyl proteinase, Scytalidium sp. pepstatin-insensitive carboxyl proteinase A

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.23 Aspartic endopeptidases

                3.4.23.31 Scytalidopepsin A

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Results	in table
1	CAS Registry Number
15	Inhibitors
15	KM Value [mM]
1	Localization
2	Metals/Ions
5	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
58	Organism
4	pH Optimum
1	pH Range
4	pH Stability
2	pI Value
10	Posttranslational Modification
2	Purification (Commentary)
1	Reaction
1	Reaction Type
18	Reference
5	Source Tissue
2	Specific Activity [micromol/min/mg]
72	Substrates and Products (Substrate)
9	Synonyms
2	Temperature Optimum [°C]
1	Temperature Range [°C]
6	Temperature Stability [°C]

KM Value

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KM Value on EC 3.4.23.31 - Scytalidopepsin A

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KM VALUE [mM]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

1.1

Benzyloxycarbonyl-Ala-Leu-Ala-Ala

Scytalidium lignicola

-

-

30759

3.1

Benzyloxycarbonyl-Ala-Lys-Ala-Ala-Ala

Scytalidium lignicola

-

-

30759

1.5

Benzyloxycarbonyl-Ala-Phe-Gly-Ala

Scytalidium lignicola

-

-

30759

0.6

Benzyloxycarbonyl-Ala-Phe-Leu-Ala

Scytalidium lignicola

-

-

30759

1.3

Benzyloxycarbonyl-Gly-Phe-Leu-Ala

Scytalidium lignicola

-

-

30759

2.5

Benzyloxycarbonyl-Lys-Ala-Ala-Ala

Scytalidium lignicola

-

-

30759

2.1

Benzyloxycarbonyl-Lys-Leu-Ala-Ala

Scytalidium lignicola

-

-

30759

3.7

benzyloxycarbonyl-Phe-Glu-Ala-Ala

Scytalidium lignicola

-

-

30759

0.8

benzyloxycarbonyl-Phe-Lys-Ala-Ala

Scytalidium lignicola

-

-

30759

1.6

Benzyloxycarbonyl-Phe-Tyr-Ala-Ala

Scytalidium lignicola

-

-

30759

0.5 - 1

Succinyl-Phe-Arg-Ala-Phe 4-nitrophenyl ester

3 entries

additional information

additional information

2 entries

-

0.5

Succinyl-Phe-Arg-Ala-Phe 4-nitrophenyl ester

Scytalidium lignicola

-

enzyme form C

30756

1

Succinyl-Phe-Arg-Ala-Phe 4-nitrophenyl ester

Scytalidium lignicola

-

benzyloxycarbonyl-Phe-Leu-Ala-Ala, benzyloxycarbonyl-Ala-Ala-Lys-Ala-Ala-Ala

30759

1

Succinyl-Phe-Arg-Ala-Phe 4-nitrophenyl ester

Scytalidium lignicola

-

enzyme form A-2

30756

additional information

additional information

Scytalidium lignicola

-

kinetic studies with synthetic peptides

30759

-

additional information

additional information

Scytalidium lignicola

-

kinetic studies

30757

-