3.4.23.25: saccharopepsin

This is an abbreviated version!
For detailed information about saccharopepsin, go to the full flat file.

Word Map on EC 3.4.23.25

Reaction

Hydrolysis of proteins with broad specificity for peptide bonds. Cleaves -Leu-Leu-/-Val-Tyr bond in a synthetic substrate. Does not act on esters of Tyr or Arg =

Synonyms

Protease A, Proteinase A, EC 3.4.23.6, Yeast endopeptidase A, Saccharomyces aspartic proteinase, Aspartic proteinase yscA, Proteinase yscA, Proteinase, yeast A, Saccharomyces cerevisiae aspartic proteinase A, Yeast proteinase A, PRA, EC 3.4.23.8, Acid protease, Aspartate protease, Aspartic proteinase, vacuolar aspartic proteinase, proteinase-A, yeast proteinase, PEP4 gene product, pseudo-proteinase A, proteinase A precursor, pepsin-like aspartic proteinase, preproPrA, proPrA, Pep4p vacuolar proteinase, Pep4p, saccharopepsin, yeast aspartic proteinase A, Pep4

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.23 Aspartic endopeptidases
                3.4.23.25 saccharopepsin

pH Optimum

pH Optimum on EC 3.4.23.25 - saccharopepsin

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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
2.4
-
casein, azocasein
2.4 - 2.8
-
and 5.5-6.0, casein
2.7 - 3.2
-
hemoglobin
3.2
-
hemoglobin
4.7
-
inactivation of nucleosidase
5 - 5.5
-
succinyl-Arg-Pro-Phe-His-Leu-Leu-Val-Tyr 4-methylcoumarin 7-amide
5.5 - 6
-
and 2.4-2.8, casein
6
-
casein, azocasein
additional information
-
the pH-optimum for hydrolysis of protein substrates can be shifted to about 5 with 4-6 M urea