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3.4.23.25: saccharopepsin

This is an abbreviated version!
For detailed information about saccharopepsin, go to the full flat file.

Word Map on EC 3.4.23.25

Reaction

Hydrolysis of proteins with broad specificity for peptide bonds. Cleaves -Leu-Leu-/-Val-Tyr bond in a synthetic substrate. Does not act on esters of Tyr or Arg =

Synonyms

Acid protease, Aspartate protease, Aspartic proteinase, Aspartic proteinase yscA, EC 3.4.23.6, EC 3.4.23.8, EC 3.4.4.17, Pep4, PEP4 gene product, Pep4p, Pep4p vacuolar proteinase, pepsin-like aspartic proteinase, PRA, preproPrA, proPrA, Protease A, Proteinase A, proteinase A precursor, Proteinase yscA, Proteinase, yeast A, proteinase-A, pseudo-proteinase A, Saccharomyces aspartic proteinase, Saccharomyces cerevisiae aspartic proteinase A, saccharopepsin, vacuolar aspartic proteinase, yeast aspartic proteinase A, Yeast endopeptidase A, yeast proteinase, Yeast proteinase A

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.23 Aspartic endopeptidases
                3.4.23.25 saccharopepsin

Inhibitors

Inhibitors on EC 3.4.23.25 - saccharopepsin

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1,2-epoxy-3-(4-nitrophenoxy) propane
-
-
1,2-epoxy-3-(4-nitrophenoxy)propane
-
-
1,2-epoxy-3-(p-nitrophenoxy) propane
-
2-mercaptoethanol
-
-
CP-108,420
CP-72,647
CP-81,198
CP-81,282
Diazoacetyl-D,L-norleucine methyl ester
-
Diazoacetyl-DL-norleucine methyl ester
HgCl2
-
complete inhibition at 0.05 mM
IA3
-
IA3 inhibitor
-
-
-
iodoacetate
-
weak inhibitor
leupeptin
-
strong inhibitor
natural aspartic proteinase inhibitor IA3
-
-
-
natural aspartic proteinase inhibitor IA4
-
-
-
p-chloromercuribenzoic acid
-
complete inhibition at 0.1 mM
PD-129,541
PD-133,450
pepstatin A
-
-
PMSF
-
weak inhibitor
potato aspartic proteinase inhibitor
-
-
-
protein IA3
-
Saccharomyces cerevisiae protein
-
protein IA3 mutant 2-34
-
-
-
protein IA3 mutant M31-M32
-
-
-
Specific proteinase inhibitor from yeast
-
tomato aspartic proteinase inhibitor
-
-
-
additional information
-
insensitive to diisopropylphosphofluoridate, metal chelating agents and thiol poisons
-