3.4.23.25: saccharopepsin

This is an abbreviated version!
For detailed information about saccharopepsin, go to the full flat file.

Word Map on EC 3.4.23.25

3.4.23.25

proteinases

3.4.23.6

zymogen

pepstatin

ia3

endothiapepsin

rhizopuspepsin

food industry

medicine

Reaction

Hydrolysis of proteins with broad specificity for peptide bonds. Cleaves -Leu-Leu-/-Val-Tyr bond in a synthetic substrate. Does not act on esters of Tyr or Arg =

Synonyms

Acid protease, Aspartate protease, Aspartic proteinase, Aspartic proteinase yscA, EC 3.4.23.6, EC 3.4.23.8, EC 3.4.4.17, Pep4, PEP4 gene product, Pep4p, Pep4p vacuolar proteinase, pepsin-like aspartic proteinase, PRA, preproPrA, proPrA, Protease A, Proteinase A, proteinase A precursor, Proteinase yscA, Proteinase, yeast A, proteinase-A, pseudo-proteinase A, Saccharomyces aspartic proteinase, Saccharomyces cerevisiae aspartic proteinase A, saccharopepsin, vacuolar aspartic proteinase, yeast aspartic proteinase A, Yeast endopeptidase A, yeast proteinase, Yeast proteinase A

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.23 Aspartic endopeptidases

3.4.23.25 saccharopepsin

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Results	in table
2	Activating Compound
18	AA Sequence
9	Application
1	CAS Registry Number
5	Cloned(Commentary)
6	Crystallization (Commentary)
3	Expression
2	General Information
3	General Stability
1	IC50 Value
50	Inhibitors
47	Ki Value [mM]
39	KM Value [mM]
21	Localization
18	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
76	Organism
12	PDB ID
14	pH Optimum
4	pH Range
4	pH Stability
9	Posttranslational Modification
5	Protein Variants
13	Purification (Commentary)
3	Reaction
1	Reaction Type
43	Reference
1	Source Tissue
4	Specific Activity [micromol/min/mg]
2	Storage Stability
115	Substrates and Products (Substrate)
15	Subunits
75	Synonyms
2	Temperature Optimum [°C]
3	Temperature Stability [°C]
40	Turnover Number [1/s]

Cloned

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Cloned on EC 3.4.23.25 - saccharopepsin

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2 entries

construction of different PEP4, PRB1, and PRC1 deficiency mutants

Saccharomyces cerevisiae

683085

expression in Xenopus oocytes

Saccharomyces cerevisiae

30708

overproduction-induced mislocation of the enzyme protein allows isolation of its structural gene

Saccharomyces cerevisiae

30699