3.4.23.19: Aspergillopepsin II
This is an abbreviated version!
For detailed information about Aspergillopepsin II, go to the full flat file.
Word Map on EC 3.4.23.19
Reaction
preferential cleavage in B chain of insulin: Asn3-/-Gln, Gly13-/-Ala, Tyr26-/-Thr =
Synonyms
acid proteinase, acid proteinase A, AGP, aspergilloglutamic peptidase, Aspergillus niger var. macrosporus aspartic proteinase, Aspergillus proteinase A, EC 3.4.23.6, More, non-pepsin type acid proteinase, Proctase A, Proteinase A
ECTree
3.4.23.19 Aspergillopepsin IIAdvanced search results
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results (Inhibitors
Inhibitors on EC 3.4.23.19 - Aspergillopepsin II
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INHIBITOR 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
synthetic propeptides
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wild-type sequence Ala1-Asn41 and diverse truncated or mutated propeptides, overview, Ala1-Asn41 shows specific competitive inhibition, while mutants, especially R19A and H20A, show weak inhibitory effects, detailed overview
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Diazoacetyl-DL-norleucine methyl ester
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in the presence of Cu2+; pH-profile
additional information
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no inhibition by diisopropyl fluorophosphate; no inhibition by pepstatin
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additional information
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insensitive to pepstatin, diazoacetyl-DL-norleucine methyl ester, and 1,2-epoxy-3-(p-nitrophenoxy)propane
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additional information
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no inhibition by pepstatin, DAN, and 1.2-epoxy-3-(4-nitrophenoxy)propane
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