3.4.22.41: cathepsin F
This is an abbreviated version!
For detailed information about cathepsin F, go to the full flat file.
Word Map on EC 3.4.22.41
-
3.4.22.41
-
cathepsins
-
diagnostics
-
westermani
-
viroid
-
paragonimus
-
f-like
-
food industry
-
metalloproteinase-10
-
cystatin-like
-
viverrini
-
medicine
- 3.4.22.41
- cathepsins
- diagnostics
- westermani
- viroid
- paragonimus
-
f-like
- food industry
- metalloproteinase-10
-
cystatin-like
- viverrini
- medicine
Reaction
The recombinant enzyme cleaves synthetic substrates with Phe and Leu (better than Val) in P2, with high specificity constant (kcat/Km) comparable to that of cathepsin L =
Synonyms
cat F, CatF, cathepsin f, cathepsin F-1, CATSF, CF-1, CF-11, CF-4, CF-6, cf1, CtF, CTSF, Ov-CF-1, PwCP1, PwCP10, PwCP11, PwCP2, PwCP3, PwCP4, PwCP5, PwCP6, PwCP7, PwCP8, PwCP9, Tci-CF-1
ECTree
Advanced search results
Posttranslational Modification
Posttranslational Modification on EC 3.4.22.41 - cathepsin F
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
glycoprotein
additional information
glycoprotein
four putative N-glycosylation site, one in the propeptide at Asn13, three in the mature region at Asn185, Asn196, Asn258 , no evidence of usage for in vivo glycosylation
glycoprotein
five potential glycosylation sites at positions 141p, 176p of the signal sequence and 97, 108, 170 of the mature enzyme
glycoprotein
-
the enzyme contains three potential N-linked glycosylation sites in the mature region: N97 and N108 and N170
recombinant expression results in zymogen which needs to be activated, recombinant Ov-CF-1 does not autocatalytically process and activate at pH 4.5, activation can be accomplished by Fasciola hepatica cathepsin L1
additional information
-
recombinant expression results in zymogen which needs to be activated, recombinant Ov-CF-1 does not autocatalytically process and activate at pH 4.5, activation can be accomplished by Fasciola hepatica cathepsin L1