3.4.22.41: cathepsin F

This is an abbreviated version!
For detailed information about cathepsin F, go to the full flat file.

Word Map on EC 3.4.22.41

Reaction

The recombinant enzyme cleaves synthetic substrates with Phe and Leu (better than Val) in P2, with high specificity constant (kcat/Km) comparable to that of cathepsin L =

Synonyms

CATSF, CatF, cathepsin f, CTSF, cat F, cathepsin F-1, Tci-CF-1, cf1, Ov-CF-1, CF-1, CtF, CF-4, CF-11, CF-6, PwCP1, PwCP2, PwCP3, PwCP4, PwCP5, PwCP6, PwCP7, PwCP8, PwCP9, PwCP10, PwCP11

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.41 cathepsin F

Natural Substrates Products

Natural Substrates Products on EC 3.4.22.41 - cathepsin F

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
Hemoglobin + H2O
?
show the reaction diagram
-
cathepsin F and cathepsin B can work in concert to hydrolyse hemoglobin at low pH
-
-
?
Ii-MHC class II complex + H2O
?
show the reaction diagram
-
-
-
-
?
LAMP 2 protein + H2O
?
show the reaction diagram
-
-
-
-
?
additional information
?
-