bleomycin hydrolase

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Word Map on EC


Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred =


More, PEPC, aminopeptidase C, hydrolase H, BANA-hydrolase, Blh1p, Gal6p, aminopeptidase H, Bleomycin hydrolase, BLM hydrolase, BMH, ApsC, BH, yeast cysteine protease, yBLH, homocysteine thiolactonase, Hcy-thiolactonase, HTLase, BLH, BH protein, BLMH protein, citrulline aminopeptidase, Blmh


     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
       bleomycin hydrolase